Department of Pathology, Atatürk University, Faculty of Medicine, Erzurum, Turkiye.
Department of Pathology, University of Health Sciences Ankara Atatürk Sanatoryum Training and Research Hospital, Ankara, Turkiye.
Br J Hosp Med (Lond). 2024 Sep 30;85(9):1-9. doi: 10.12968/hmed.2024.0174. Epub 2024 Sep 19.
Pulmonary mucous gland adenomas (MGAs) originating in mucous-secreting cells in the bronchi are extremely rare benign tumours. Pulmonary chondroid hamartomas (PCHs) are the most common benign neoplasms of mesenchymal origin of the lung. This study reports an unusual case where MGA and PCH coexisted in a peripheral intra-parenchymal location. A patient with a 1-cm non-specific nodule in the left lung on a computed tomography scan underwent wedge resection. Microscopically, mesenchymal elements consisting of fat and cartilage tissue were observed. Mucous glands were present around these mesenchymal elements. No cellular atypia or mitosis was observed. This allowed for complete treatment without the need for a segmentectomy.
肺黏液腺腺瘤(MGA)起源于支气管的黏液分泌细胞,是极其罕见的良性肿瘤。肺软骨瘤样错构瘤(PCH)是肺内最常见的间叶组织来源的良性肿瘤。本研究报告了一个不常见的病例,即 MGA 和 PCH 同时存在于肺外周实质部位。一名患者在 CT 扫描中发现左肺 1cm 大小的非特异性结节,行楔形切除术。镜下观察到由脂肪和软骨组织组成的间叶成分。这些间叶成分周围存在黏液腺。未见细胞异型性或有丝分裂。因此,无需行肺段切除术即可完全治愈。