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川崎病伴发热和黄疸:病例报告。

Kawasaki Disease Presenting with Fever and Jaundice: Case Report.

机构信息

Department of Pediatrics, Taiyuan Children's Hospital & Taiyuan Maternity and Child Health Care Hospital, Taiyuan, Shanxi, China.

出版信息

Br J Hosp Med (Lond). 2024 Sep 30;85(9):1-12. doi: 10.12968/hmed.2024.0288.

Abstract

Kawasaki disease (KD), which is also known as cutaneous mucosal lymph node syndrome, is an acute, self-limiting, necrotizing vasculitis with unclear cause that primarily affects small- and medium-sized blood vessels and most commonly affects children aged 6 months to 5 years. Currently, diagnosis is based primarily on typical clinical symptoms. Approximately 15%-20% of patients are highly suspected of having KD; however, they do not match the diagnostic criteria for typical KD, which is referred to as incomplete Kawasaki disease (IKD), and this has become a major challenge in the diagnosis and treatment of KD. We describe a case of a 7-year-old boy who had a fever and jaundice as his initial symptoms. After a series of clinical laboratory and imaging examinations and marked improvement of symptoms after treatment with intravenous immunoglobulin (IVIG), IKD was considered as the diagnosis. When children present with jaundice and fever, physicians should consider KD as a possible diagnosis to ensure early detection and treatment of the disease.

摘要

川崎病(KD),又称皮肤黏膜淋巴结综合征,是一种病因不明的急性、自限性、坏死性小血管炎,主要影响中小血管,最常发生于 6 个月至 5 岁的儿童。目前,主要根据典型的临床症状进行诊断。约 15%-20%的患者高度怀疑患有 KD,但不符合典型 KD 的诊断标准,这被称为不完全川崎病(IKD),这已成为 KD 诊断和治疗的一大挑战。我们描述了一例 7 岁男孩,以发热和黄疸为首发症状。经过一系列临床实验室和影像学检查,以及静脉注射免疫球蛋白(IVIG)治疗后症状明显改善,考虑为 IKD。当儿童出现黄疸和发热时,医生应考虑 KD 作为可能的诊断,以确保早期发现和治疗该疾病。

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