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优化成人乳糜泻的诊断:当前证据和未来方向。

Optimising the Diagnosis of Adult Coeliac Disease: Current Evidence and Future Directions.

机构信息

Academic Unit of Gastroenterology, Sheffield Teaching Hospitals, Sheffield, UK.

Division of Clinical Medicine, School of Medicine and Population Health, University of Sheffield, Sheffield, UK.

出版信息

Br J Hosp Med (Lond). 2024 Sep 30;85(9):1-21. doi: 10.12968/hmed.2024.0362.

DOI:10.12968/hmed.2024.0362
PMID:39347683
Abstract

Coeliac disease is a common autoimmune disorder that affects nearly 1% of the general population. Current diagnostic strategies involve active case finding, serological tests, and endoscopy with biopsies. However, many patients with coeliac disease remain undiagnosed due to a wide gap between clinical guidelines and real-world practice in the diagnosis of adult coeliac disease. This highlights the need for increased education, training, and targeted quality-improvement interventions to optimise the diagnosis of coeliac disease.

摘要

乳糜泻是一种常见的自身免疫性疾病,影响近 1%的普通人群。目前的诊断策略包括主动病例发现、血清学检测和内镜活检。然而,由于临床指南与成人乳糜泻诊断的实际情况之间存在较大差距,许多乳糜泻患者仍未得到诊断。这凸显出需要加强教育、培训和有针对性的质量改进干预措施,以优化乳糜泻的诊断。

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