Nigi Laura, Simon Batzibal Maria De Los Angeles, Cataldo Dorica, Dotta Francesco
Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, Italy.
Diabetes and Metabolic Diseases Unit, Azienda Ospedaliera Universitaria Senese, Siena, Italy.
Diabetes Ther. 2024 Dec;15(12):2557-2568. doi: 10.1007/s13300-024-01656-w. Epub 2024 Sep 30.
Time in tight range (TITR) is an emerging and valuable metric for assessing normoglycemia. The latest advancement in automated insulin delivery (AID) systems, the advanced hybrid closed-loop (AHCL) systems, are particularly noteworthy for managing type 1 diabetes (T1D) and enhancing glycemic control.
In a real-world clinical setting, we carried out a retrospective evaluation of TITR in 42 adult subjects with T1D using the AHCL Minimed™ 780G system over a 12-month period.
Within just 14 days of activating the automatic mode, the AHCL Minimed™ 780G system showed rapid improvement in TITR, and in the other continuous glucose monitoring (CGM) metrics. This improvement persisted over 12 months, achieving the proposed 45-50% range for effective glycemic control.
The AHCL Minimed™ 780G system significantly enhances TITR, demonstrating continuous improvement throughout a 12-month follow-up period.
血糖处于严格范围内的时间（TITR）是评估血糖正常的一个新兴且有价值的指标。自动胰岛素输注（AID）系统的最新进展，即先进混合闭环（AHCL）系统，在管理1型糖尿病（T1D）和改善血糖控制方面尤其值得关注。
在真实临床环境中，我们对42名成年T1D患者使用AHCL美敦力™780G系统进行了为期12个月的TITR回顾性评估。
在激活自动模式后的短短14天内，AHCL美敦力™780G系统在TITR以及其他连续血糖监测（CGM）指标方面均显示出快速改善。这种改善在12个月内持续存在，达到了有效血糖控制所建议的45%至50%的范围。
AHCL美敦力™780G系统显著提高了TITR，在12个月的随访期内持续改善。
