AlBahrani Salma, Saad Mustafa, Alqahtani Jaber S, Almoosa Zainab, Alabdulla Mohammed, Algezery Mohammed, AlShehri Sondos, Al-Tawfiq Jaffar A
Infectious Disease Unit, Specialty Internal Medicine, King Fahd Military Medical Complex, Dhahran, Saudi Arabia.
College of medicine-Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
J Epidemiol Glob Health. 2024 Dec;14(4):1371-1380. doi: 10.1007/s44197-024-00297-3. Epub 2024 Sep 30.
Although there is ample proof of the advantages of infection prevention and Control (IPC) in acute-care hospitals, there is still some questions about the efficacy of IPC interventions for multidrug-resistant organisms (MDROs), and there is a need for the development of evidence-based practices. No healthcare facility has found a single effective technique to reduce MDRO. However, a multicomponent intervention that included improved barrier protection, chlorhexidine bathing, microbiological monitoring, and staff involvement significantly decreased the likelihood of infection in the patient surroundings with multidrug-resistant organisms. A practical strategy suited to reducing the burden of MDROs and their transmission potential in the critical care unit must be established in light of the global development of AMR. In this review, we summarize key findings of a multicomponent approaches to reduce MDROs in critical care units.
尽管在急症医院中，感染预防与控制（IPC）的优势已有充分证据，但对于IPC干预措施针对多重耐药菌（MDROs）的效果仍存在一些疑问，且需要制定循证实践。没有任何一家医疗机构找到单一有效的技术来减少MDROs。然而，一项包括改善屏障防护、洗必泰沐浴、微生物监测及员工参与的多组分干预措施显著降低了患者周围环境中出现多重耐药菌感染的可能性。鉴于抗菌药物耐药性（AMR）的全球发展态势，必须制定一项适合于减轻重症监护病房中MDROs负担及其传播可能性的实用策略。在本综述中，我们总结了多组分方法减少重症监护病房中MDROs的关键研究结果。
