University of Washington School of Medicine, Seattle.
Abbott Diabetes Care, Alameda, CA.
J Manag Care Spec Pharm. 2024 Oct;30(10-b Suppl):S21-S29. doi: 10.18553/jmcp.2024.30.10-b.s21.
The increasing prevalence of diabetes in the United States continues to drive a steady rise in health care resource utilization, especially emergency department visits and all-cause hospitalizations, and the associated costs.
To investigate the impact of continuous glucose monitoring (CGM) on emergency department visits and all-cause hospitalizations among Medicaid beneficiaries with type 2 diabetes (T2D) treated with multiple daily insulin injections (MDIs) or basal insulin therapy (BIT) in a real-world setting.
In this retrospective, 12-month analysis, we used the Inovalon Insights claims dataset to evaluate the effects of CGM acquisition on emergency department visits and all-cause hospitalizations in the Managed Medicaid population. The analysis included 44,941 beneficiaries with T2D who were treated with MDIs (n = 35,367) or BIT (n = 9,574). Primary outcomes were changes in the number of emergency department visits and all-cause hospitalizations following 6 months after acquisition of CGM (post-index period) compared with 6 month prior to CGM acquisition (pre-index period). The first claim for CGM was the index date. Inclusion criteria were as follows: aged younger than 65 years, diagnosis of T2D, claims for short- or rapid-acting insulin (MDI group) or basal insulin (not rapid-acting) (BIT group), acquisition of a CGM device between January 1, 2017, and September 30, 2022, and continuous enrollment in their health plan throughout the pre-index and post-index periods.
In the MDI group, all-cause inpatient hospitalization rates decreased from 3.25 to 2.29 events/patient-year (hazard ratio = 0.12; 95% CI = 0.11-0.13; < 0.001) and emergency department visit rates decreased from 2.15 to 1.86 events/patient-year (hazard ratio = 0.52; 95% CI = 0.50-0.53; < 0.001). In the BIT group, all-cause inpatient hospitalization rates decreased from 1.63 to 1.39 events/patient-year (hazard ratio = 0.11; 95% CI = 0.09-0.12; < 0.001) and emergency department visit rates decreased from 1.60 to 1.43 events/patient-year (hazard ratio = 0.47; 95% CI = 0.44-0.50; < 0.001).
Acquisition of CGM is associated with significant reductions in emergency department visits and all-cause hospitalizations among people with T2D treated with MDIs or BIT.
美国糖尿病患病率的不断上升持续推动着医疗资源利用的稳步增长,尤其是急诊就诊次数和全因住院率的增加,以及相关的成本增加。
在真实环境中,调查连续血糖监测(CGM)对接受多次每日胰岛素注射(MDI)或基础胰岛素治疗(BIT)的 2 型糖尿病(T2D)医疗补助受益人的急诊就诊次数和全因住院率的影响。
在这项回顾性的 12 个月分析中,我们使用了 Inovalon Insights 索赔数据集,评估了 CGM 获得对管理型医疗补助人群中 T2D 患者急诊就诊次数和全因住院率的影响。该分析包括 44941 名接受 MDI(n=35367)或 BIT(n=9574)治疗的 T2D 患者。主要结局是在 CGM 获得后 6 个月(索引后期)与 CGM 获得前 6 个月(索引前期)相比,急诊就诊次数和全因住院次数的变化。CGM 的首次索赔为索引日期。纳入标准如下:年龄小于 65 岁,诊断为 T2D,有短期或速效胰岛素(MDI 组)或基础胰岛素(非速效)(BIT 组)的索赔,在 2017 年 1 月 1 日至 2022 年 9 月 30 日期间获得 CGM 设备,并且在索引前期和索引后期都连续参加他们的健康计划。
在 MDI 组中,全因住院率从 3.25 降至 2.29 例/患者年(风险比=0.12;95%置信区间=0.11-0.13;<0.001),急诊就诊率从 2.15 降至 1.86 例/患者年(风险比=0.52;95%置信区间=0.50-0.53;<0.001)。在 BIT 组中,全因住院率从 1.63 降至 1.39 例/患者年(风险比=0.11;95%置信区间=0.09-0.12;<0.001),急诊就诊率从 1.60 降至 1.43 例/患者年(风险比=0.47;95%置信区间=0.44-0.50;<0.001)。
CGM 的获得与接受 MDI 或 BIT 治疗的 T2D 患者的急诊就诊次数和全因住院次数的显著减少相关。