Bülbül Ogün, Bülbül Hande Melike, Kaba Esat
Recep Tayyip Erdogan University, Faculty of Medicine, Department of Nuclear Medicine, Rize, Turkey.
Recep Tayyip Erdogan University, Faculty of Medicine, Department of Radiology, Rize, Turkey.
Abdom Radiol (NY). 2025 Mar;50(3):1467-1474. doi: 10.1007/s00261-024-04619-8. Epub 2024 Sep 30.
ChatGPT has recently been the subject of many studies, and its responses to medical questions have been successful. We examined ChatGPT-4's evaluation of structured Ga prostate-specific membrane antigen (PSMA) PET/CT reports of newly diagnosed prostate cancer patients.
Ga PSMA PET/CT reports of 164 patients were entered to ChatGPT-4. ChatGPT-4 was asked to respond the following questions according to the PET/CT reports: 1-Has the cancer in the prostate extended to organs adjacent to the prostate? 2-Has the cancer in the prostate spread to neighboring lymph nodes? 3-Has the cancer in the prostate spread to lymph nodes in distant areas? 4-Has the cancer in the prostate spread to the bones? 5-Has the cancer in the prostate spread to other organs? ChatGPT-4's responses were scored on a Likert-type scale for clarity and accuracy.
The mean scores for clarity were 4.93 ± 0.32, 4.95 ± 0.25, 4.96 ± 0.19, 4.99 ± 0.11, and 4.96 ± 0.30, respectively. The mean scores for accuracy were 4.87 ∓ 0.61, 4.87 ∓ 0.62, 4.79 ± 0.83, 4.96 ± 0.25, and 4.93 ± 0.45, respectively. Patients with distant lymphatic metastases had a lower mean accuracy score than those without (4.28 ± 1.45 vs. 4.94 ± 0.39; p < 0.001). ChatGPT-4's responses in 13 patients (8%) had the potential for harmful information.
ChatGPT-4 successfully interprets structured Ga PSMA PET/CT reports of reports of newly diagnosed prostate cancer patients. However, it is unlikely that ChatGPT-4 evaluations will replace physicians' evaluations today, especially since it can produce fabricated information.
ChatGPT最近成为众多研究的对象,其对医学问题的回答很成功。我们研究了ChatGPT-4对新诊断前列腺癌患者的结构化镓前列腺特异性膜抗原(PSMA)PET/CT报告的评估情况。
将164例患者的镓PSMA PET/CT报告输入ChatGPT-4。要求ChatGPT-4根据PET/CT报告回答以下问题:1-前列腺癌是否已扩散至前列腺邻近器官?2-前列腺癌是否已扩散至邻近淋巴结?3-前列腺癌是否已扩散至远处淋巴结?4-前列腺癌是否已扩散至骨骼?5-前列腺癌是否已扩散至其他器官?ChatGPT-4的回答根据清晰度和准确性在李克特量表上进行评分。
清晰度的平均得分分别为4.93±0.32、4.95±0.25、4.96±0.19、4.99±0.11和4.96±0.30。准确性的平均得分分别为4.87∓0.61、4.87∓0.62、4.79±0.83、4.96±0.25和4.93±0.45。有远处淋巴转移的患者平均准确性得分低于无远处淋巴转移的患者(4.28±1.45对4.94±0.39;p<0.001)。ChatGPT-4对13例患者(8%)的回答存在产生有害信息的可能性。
ChatGPT-4成功解读了新诊断前列腺癌患者的结构化镓PSMA PET/CT报告。然而,目前ChatGPT-4的评估不太可能取代医生的评估,尤其是因为它可能产生虚假信息。