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分比 CO2 激光治疗丘疹性痤疮瘢痕的疗效及不良反应:35 例回顾性研究。

Efficacy and adverse reactions of fractional CO2 lasers for treating papular acne scars: a retrospective study of 35 patients.

机构信息

Department of Dermatology, Qingdao Municipal Hospital&Qingdao Hospital, University of Health and Rehabilitation Sciences(Qingdao Municipal Hospital), Qingdao, Shandong, China.

出版信息

Lasers Med Sci. 2024 Sep 30;39(1):246. doi: 10.1007/s10103-024-04203-y.

DOI:10.1007/s10103-024-04203-y
PMID:39348030
Abstract

Papular acne scars are a special type of acne scar, and the prevalence and treatment of this disease have rarely been reported in the literature; moreover, the prevalence of this disease is often neglected, and treatment is difficult. Our study revealed a high prevalence of this type of acne scar in the clinic and explored an effective and safe method. This retrospective study aimed to analyse the prevalence of papular acne scarring among patients attending our Dermatology Laser Clinic and evaluate the clinical efficacy of fractional CO2 lasers. We retrieved the data of 370 patients with acne scarring who visited our hospital between April 2021 and November 2022 and analysed the prevalence of papillary acne scarring among them. Among these patients, 35 underwent CO laser treatment using an artificial grid pattern. A total of three treatments were administered, with a two-month interval between each session. Scar assessment was conducted using the Global Scar Scale (GSS) and the Acne Scar Clinical Assessment (ECCA) scale, along with physician visual evaluation and patient satisfaction surveys, both before the first treatment and one month after the final treatment. Adverse reactions were recorded during follow-up visits after each treatment. Among the 370 patients with acne scarring, 128 exhibited papular acne scarring, resulting in a prevalence rate of 34.6%. Among them, 37.5% were male and 32.6% were female. A total of 90.6% of patients had combined other types of acne scarring, while 9.4% had papular acne scarring exclusively. Following CO laser grid treatment, there was a significant reduction in GSS scores and ECCA values, accompanied by a noticeable improvement in physician visual evaluation and patient satisfaction scores. Papular acne scarring has a relatively high incidence rate, and there is no significant sex difference. It often coexists with other types of acne scarring. CO laser treatment using an artificial grid pattern effectively improved papular acne scarring with a good safety profile.

摘要

丘疹性痤疮瘢痕是一种特殊类型的痤疮瘢痕,其发病率和治疗方法在文献中鲜有报道;此外,该病的发病率常被忽视,治疗较为困难。我们的研究揭示了这种类型的痤疮瘢痕在临床上的高发病率,并探索了一种有效且安全的方法。这项回顾性研究旨在分析我们皮肤科激光诊所就诊患者中丘疹性痤疮瘢痕的患病率,并评估分 106 二氧化碳激光的临床疗效。我们回顾性分析了 2021 年 4 月至 2022 年 11 月期间在我院就诊的 370 例痤疮瘢痕患者的数据,分析了其中丘疹性痤疮瘢痕的患病率。其中 35 例患者接受了人工格栅模式的 CO2 激光治疗。共进行了 3 次治疗,每次治疗间隔 2 个月。在首次治疗前和末次治疗后 1 个月,采用全球瘢痕量表(GSS)、痤疮瘢痕临床评估量表(ECCA)、医生视觉评估和患者满意度调查对瘢痕进行评估。在每次治疗后随访时记录不良反应。在 370 例痤疮瘢痕患者中,128 例存在丘疹性痤疮瘢痕,患病率为 34.6%。其中男性占 37.5%,女性占 32.6%。90.6%的患者同时存在其他类型的痤疮瘢痕,9.4%的患者仅存在丘疹性痤疮瘢痕。经 CO2 激光格栅治疗后,GSS 评分和 ECCA 值显著降低,医生视觉评估和患者满意度评分显著提高。丘疹性痤疮瘢痕的发病率相对较高,且男女之间无显著差异。它常与其他类型的痤疮瘢痕共存。人工格栅模式的 CO2 激光治疗可有效改善丘疹性痤疮瘢痕,且安全性良好。

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How I Do It: Treatment of Papular Acne Scars of the Nose.我的做法:鼻部丘疹性痤疮瘢痕的治疗
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