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转移性肠道腺癌：罕见累及下颌骨病例

Metastatic Intestinal Adenocarcinoma: A Rare Case Involving the Mandible.

机构信息

Department of Oral and Maxillofacial Pathology, Manipal College of Dental Sciences, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.

Department of Oral and Maxillofacial Surgery, Manipal College of Dental Sciences, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.

出版信息

Head Neck Pathol. 2024 Sep 30;18(1):91. doi: 10.1007/s12105-024-01697-4.

DOI:10.1007/s12105-024-01697-4
PMID:39348031
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11442947/
Abstract

BACKGROUND

Metastatic intestinal adenocarcinoma involving the mandible is rare, posing diagnostic challenges because of its unusual presentation.

CASE PRESENTATION

A 55-year-old male presented with a rapidly growing mass in the right mandible, accompanied by facial asymmetry and vestibular obliteration. Histopathological examinations revealed features consistent with adenocarcinoma. Immunohistochemical analysis supported the diagnosis of intestinal adenocarcinoma, with subsequent metastasis confirmed by PET scan findings.

DIAGNOSIS

The lesion was conclusively diagnosed as intestinal adenocarcinoma metastasizing to the mandible.

MANAGEMENT

The patient pursued treatment at a government facility, leading to a loss of follow-up.

摘要

背景

转移性结直肠腺癌累及下颌骨较为罕见，因其表现不典型，故诊断具有挑战性。

病例介绍

一名 55 岁男性因右侧下颌骨迅速生长的肿块、面部不对称和前庭闭塞就诊。组织病理学检查显示符合腺癌的特征。免疫组化分析支持肠腺癌的诊断，随后 PET 扫描结果证实转移。

诊断

该病变最终诊断为转移性结直肠腺癌至下颌骨。

治疗

患者在政府机构接受治疗，随后失去随访。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b2e/11442947/fee420a71d1e/12105_2024_1697_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b2e/11442947/cde475155462/12105_2024_1697_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b2e/11442947/e5f090160abd/12105_2024_1697_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b2e/11442947/b6c754272b2a/12105_2024_1697_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b2e/11442947/10af419ebf8d/12105_2024_1697_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b2e/11442947/c5e6813590dd/12105_2024_1697_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b2e/11442947/fee420a71d1e/12105_2024_1697_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b2e/11442947/cde475155462/12105_2024_1697_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b2e/11442947/e5f090160abd/12105_2024_1697_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b2e/11442947/b6c754272b2a/12105_2024_1697_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b2e/11442947/10af419ebf8d/12105_2024_1697_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b2e/11442947/c5e6813590dd/12105_2024_1697_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b2e/11442947/fee420a71d1e/12105_2024_1697_Fig6_HTML.jpg

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本文引用的文献

1
Primary intestinal-type adenocarcinoma of the buccal mucosa: A case report and literature review.原发性口腔黏膜肠型腺癌 1 例报告并文献复习
Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Feb;127(2):e61-e70. doi: 10.1016/j.oooo.2018.05.010. Epub 2018 May 30.
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Primary intestinal-type adenocarcinoma of the oral tongue: Case report and review of histologic origin and oncologic management.原发性舌口腔型肠型腺癌：病例报告及组织起源和肿瘤治疗的回顾。
Head Neck. 2018 Jul;40(7):E68-E72. doi: 10.1002/hed.25203. Epub 2018 May 13.
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Intestinal-Type Adenocarcinoma: Classification, Immunophenotype, Molecular Features and Differential Diagnosis.
肠型腺癌：分类、免疫表型、分子特征及鉴别诊断
Head Neck Pathol. 2017 Sep;11(3):295-300. doi: 10.1007/s12105-017-0800-7. Epub 2017 Mar 20.
4
Metastatic adenocarcinoma of the colon presenting as a mass in the mandible.以颌骨肿块为表现的结肠转移性腺癌。
Head Neck. 2005 Aug;27(8):729-32. doi: 10.1002/hed.20224.