2023 年巴塞罗那基层医疗中的抗生素使用情况，以及通过调整药盒大小以符合现行指南来减少抗生素使用的潜力。
Antibiotic use in Barcelona in 2023 in primary care and the potential reduction by adjusting box sizes to current guidelines.
机构信息
Carl Llor, Via Roma Health Centre. c. Manso, 19, 3rd floor. 08015 Barcelona. Spain.
出版信息
Rev Esp Quimioter. 2024 Dec;37(6):504-508. doi: 10.37201/req/054.2024. Epub 2024 Oct 1.
OBJECTIVE
Prior research has not examined the size of antibiotic packages prescribed. We assessed 2023 prescription rates in Barcelona and the most prescribed presentations in pharmacies, while evaluating potential reductions if all amoxicillin and amoxicillin/clavulanate containers had 20 doses.
METHODS
Antibiotics prescribed by primary care doctors working for the Catalonian Health Institute in Barcelona in 2023 were analysed by calculating the defined daily doses per 1,000 inhabitants and day (DID).
RESULTS
The observed prescribing rate was 8 DID, with penicillins accounting for 4.6 DID (57.2%). The most frequently prescribed antibiotics were amoxicillin and amoxicillin/clavulanate, making up 4.4 DID. If all the 30-dose presentations of amoxicillin and amoxicillin/clavulanate had been 20-dose containers, the total number of DIDs would have been 3.3, resulting in a reduction of 1.1 DID (25.4% less).
CONCLUSIONS
Antibiotic prescribing rate in Barcelona was low. Aligning the dosage of antibiotics with established guidelines could further reduce antibiotic consumption.
目的
先前的研究尚未考察所开抗生素处方的剂量。我们评估了 2023 年巴塞罗那的处方率和各药店最常开出的剂型，并评估了如果所有阿莫西林和阿莫西林/克拉维酸的容器均为 20 剂量剂型，潜在的减少量。
方法
通过计算每千居民和每日限定日剂量（DID）分析了巴塞罗那加泰罗尼亚卫生研究所的初级保健医生 2023 年开出的抗生素处方。
结果
观察到的处方率为 8DID，其中青霉素占 4.6DID（57.2%）。最常开出的抗生素是阿莫西林和阿莫西林/克拉维酸，占 4.4DID。如果所有 30 剂量的阿莫西林和阿莫西林/克拉维酸都为 20 剂量剂型，总 DID 数将为 3.3，减少 1.1DID（减少 25.4%）。
结论
巴塞罗那的抗生素处方率较低。使抗生素剂量与既定指南保持一致可能会进一步减少抗生素的使用。
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