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糖尿病继发肾脓肿的手术治疗及高压氧治疗的成功管理。

Successful management of renal abscess secondary to diabetes mellitus with surgical treatment and hyperbaric oxygen therapy.

机构信息

Department of Urology, Koto Hospital, Koto-ku, Tokyo, Japan.

Department of Urology, Teikyo University School of Medicine, Itabashi-ku, Tokyo, Japan.

出版信息

Undersea Hyperb Med. 2024 Third Quarter;51(3):231-235.

PMID:39348515
Abstract

Renal abscess (RA) is a collection of infective fluid in or around the renal parenchyma. It typically occurs in immunocompromised patients, including those with diabetes mellitus (DM), poor nutritional status, or steroid administration. We herein report a case of RA associated with DM in which hyperbaric oxygen (HBO) therapy greatly contributed to the resolution of this disease. The patient was an 85-year-old man with poorly controlled type 2 DM. Contrast-enhanced computed tomography for postoperative follow-up of appendiceal cancer showed a mass lesion with poor contrast enhancement extending from the upper pole of the left kidney to the dorsal side. Therefore, a diagnosis of RA was established. The lesion was percutaneously punctured, and a drainage tube was placed. Antibiotics following sensitivity testing were administered. The catheter was removed six days after its placement. However, pus discharge continued from the catheter removal site, with persistent redness around the wound. Therefore, a lumbotomy incision for abscess drainage was performed on the 49th day. However, the pus discharge persisted, and we decided to perform HBO therapy, expecting decreases in bacterial proliferation, reduction in local edema, and improvement of host defense. HBO therapy for 90 min at two atmospheres absolute was performed ten times. The amount of pus discharge decreased, and redness improved from the fifth day after HBO therapy. One month after starting HBO therapy, the wound was closed, and the pus discharge resolved completely. Four years have passed since the HBO therapy, and there have been no symptomatic or imaging relapses of RA.

摘要

肾脓肿(RA)是肾实质内或周围积聚的感染性液体。它通常发生在免疫功能低下的患者中,包括患有糖尿病(DM)、营养不良或类固醇治疗的患者。本文报告了一例与 DM 相关的 RA 病例,高压氧(HBO)治疗对该疾病的缓解有很大帮助。患者为 85 岁男性,患有未控制的 2 型糖尿病。为了对阑尾癌的术后进行随访,对患者进行了增强 CT 检查,结果显示左肾上极到背部有一个肿块,增强效果不佳。因此,诊断为 RA。对病变进行了经皮穿刺,并放置了引流管。根据药敏试验结果给予抗生素治疗。放置引流管六天后将其取出。然而,导管拔出部位仍有脓液排出,伤口周围持续发红。因此,在第 49 天进行了腰部切开脓肿引流术。然而,脓液仍持续排出,我们决定进行 HBO 治疗,期望减少细菌增殖、减轻局部水肿并改善宿主防御。进行了 10 次 2 个大气压下 90 分钟的 HBO 治疗。从 HBO 治疗的第 5 天开始,脓液排出量减少,红肿改善。开始 HBO 治疗一个月后,伤口闭合,脓液完全消失。自 HBO 治疗以来已经过去了四年,RA 没有出现症状或影像学复发。

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