Department of Urologic Surgery, University of California, Davis, 4860 Y Street, Suite 3500, Sacramento, CA 95817, USA.
Department of Urologic Surgery, University of California, Davis, 4860 Y Street, Suite 3500, Sacramento, CA 95817, USA.
Urol Clin North Am. 2024 Nov;51(4):439-444. doi: 10.1016/j.ucl.2024.06.001. Epub 2024 Jul 23.
Prostate biopsies are commonly performed for the early detection of prostate cancer and yet are associated with risks of life-threatening infections. Drug-resistant strains of Escherichia coli are the most common etiologic agents. Multiple maneuvers can reduce the risk of postbiopsy infections and sepsis during transrectal prostate biopsy including periprocedural empiric or targeted prophylactic antibiotics (based on previous rectal culture) and prebiopsy rectal cleansing with a povidone-iodine solution. The transperineal approach is associated with a very low risk of infection without requiring antibiotic prophylaxis.
前列腺活检常用于早期发现前列腺癌，但也存在危及生命的感染风险。耐多药型大肠杆菌是最常见的病原体。多项操作可降低经直肠前列腺活检术后感染和脓毒症的风险，包括术前行经验性或靶向性预防性抗生素治疗（基于之前的直肠培养结果）和经直肠使用聚维酮碘溶液进行术前直肠清洁。经会阴入路感染风险非常低，无需预防性使用抗生素。
