Yesus Y W, Akhter J E
Am J Clin Pathol. 1985 Dec;84(6):769-72. doi: 10.1093/ajcp/84.6.769.
After several transfusions with D-negative blood, an O Rh-negative women was apparently sensitized to the C and D antigens. In her prenatal workup, it became evident that she had in fact not been sensitized to D but to G, which initially appeared as anti-D plus anti-C. This sensitization pattern is an unusual occurrence in itself. Moreover, the fetus was affected significantly and was delivered at 32 1/2 weeks with moderate hemolytic disease of the newborn. Consideration is given to points regarding current methods of screening Rh-negative women for transfusion, the use of anti-Rh immune globulin in patients sensitized to anti-C and anti-G, medicolegal implications, and continuous attention to the risk-benefit ratio in decisions to use transfusions.
在多次输注D阴性血后，一名O型Rh阴性女性显然对C和D抗原致敏。在她的产前检查中，发现她实际上并未对D致敏，而是对G致敏，最初表现为抗-D加抗-C。这种致敏模式本身就不常见。此外，胎儿受到了显著影响，在32.5周时因中度新生儿溶血病而分娩。文中考虑了当前筛查Rh阴性女性输血的方法、对抗-C和抗-G致敏患者使用抗Rh免疫球蛋白的情况、法医学意义以及在决定输血时对风险效益比的持续关注等要点。
