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同种免疫孕妇中的抗G抗体:两例报告。

Anti-G antibody in alloimmunized pregnant women: Report of two cases.

作者信息

Makroo Raj Nath, Kaul Anita, Bhatia Aakanksha, Agrawal Soma, Singh Chanchal, Karna Prashant

机构信息

Department of Transfusion Medicine, Indraprastha Apollo Hospitals, Sarita Vihar, New Delhi, India.

Department of Foetal Medicine, Indraprastha Apollo Hospitals, Sarita Vihar, New Delhi, India.

出版信息

Asian J Transfus Sci. 2015 Jul-Dec;9(2):210-2. doi: 10.4103/0973-6247.162724.

DOI:10.4103/0973-6247.162724
PMID:26420948
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4562149/
Abstract

Anti-G has been reported as a possible cause of hemolytic disease of the fetus and newborn (HDFN), either independently or in association with anti-D, anti-C or both. The antibody mimics the pattern of anti-C and anti-D reactivity in the identification panel and is often present along with either or both of these antibodies. The differentiation of anti-D, -C and-G in routine pretransfusion workup is particularly essential in antenatal cases. We report two antenatal cases where anti-G was identified on advanced immunohematological workup, in addition to other alloantibodies.

摘要

抗 - G 已被报道为胎儿和新生儿溶血病(HDFN)的一个可能病因,可单独出现,也可与抗 - D、抗 - C 或两者同时存在。该抗体在鉴定谱中模拟抗 - C 和抗 - D 的反应模式,并且常与这些抗体中的一种或两种同时出现。在产前病例的常规输血前检查中,区分抗 - D、抗 - C 和抗 - G 尤为重要。我们报告了两例产前病例,除其他同种抗体外,在先进的免疫血液学检查中鉴定出了抗 - G。

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本文引用的文献

1
Development of Anti-G, Anti-C and Anti-Jk(b) in a 22-Year-Old Mother during Her Fourth Pregnancy.在第四次妊娠期间,一位 22 岁的母亲体内产生了抗-G、抗-C 和抗-Jk(b)。
Transfus Med Hemother. 2013 Jun;40(3):207-9. doi: 10.1159/000351518. Epub 2013 May 17.
2
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Hemolytic disease of the newborn due to anti-C and anti-G masquerading as anti-D.因抗-C和抗-G伪装成抗-D所致的新生儿溶血病。
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