Golden R N, James S P, Sherer M A, Rudorfer M V, Sack D A, Potter W Z
Am J Psychiatry. 1985 Dec;142(12):1459-62. doi: 10.1176/ajp.142.12.1459.
The authors describe the development of acute psychoses in four patients treated with bupropion, a unicyclic aminoketone antidepressant. In two of the cases the psychoses seemed to be affected by dose. The mechanism responsible for the psychotic reactions is unclear, although it may involve perturbation of dopaminergic systems. On the basis of their experience, the authors offer recommendations regarding the clinical use of bupropion.
作者描述了4例使用安非他酮（一种单环氨基酮类抗抑郁药）治疗的患者出现急性精神病的情况。在其中2例病例中，精神病似乎受剂量影响。虽然精神病性反应的机制尚不清楚，但可能涉及多巴胺能系统的紊乱。基于他们的经验，作者就安非他酮的临床应用提出了建议。
