Andrassy R J, DuBois T, Page C P, Patterson R S, Paredes A
Am J Surg. 1985 Dec;150(6):730-4. doi: 10.1016/0002-9610(85)90418-0.
Twenty patients who underwent extensive intraabdominal surgical procedures and placement of a needle catheter jejunostomy were prospectively studied to evaluate gastrointestinal tolerance and nutritional enhancement when fed an enteral branched-chain amino acid-enriched diet. At a mean caloric intake of 1,325.75 kcal/day (20.6 kcal/kg per day) and a mean nitrogen intake of 7.64 g/day (0.12 g/kg per day), positive nitrogen balance was achieved 2 to 3 days postoperatively. Total lymphocyte count and levels of transferrin and prealbumin increased significantly (p less than 0.05) during the study. Gastrointestinal tolerance was excellent. Plasma levels of leucine, isoleucine, and valine increased significantly during the study period but remained within the normal range.
对20例行广泛腹腔内外科手术并放置针导管空肠造口术的患者进行前瞻性研究,以评估给予肠内富含支链氨基酸的饮食时的胃肠道耐受性和营养改善情况。平均热量摄入为1325.75千卡/天(20.6千卡/千克/天),平均氮摄入量为7.64克/天(0.12克/千克/天),术后2至3天实现了正氮平衡。在研究期间,总淋巴细胞计数以及转铁蛋白和前白蛋白水平显著升高(p<0.05)。胃肠道耐受性良好。在研究期间,血浆亮氨酸、异亮氨酸和缬氨酸水平显著升高,但仍在正常范围内。