Roncaroli Federico, Giannini Caterina
Geoffrey Jefferson Brain Research Centre, Division of Neuroscience, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Division of Anatomic Pathology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Brain Pathol. 2025 Jan;35(1):e13307. doi: 10.1111/bpa.13307. Epub 2024 Sep 30.
Non-neuroendocrine tumors account for around 10% of all primary neoplasms of the sella. If meningiomas, craniopharyngiomas, and germ cell tumors are excluded, the remaining lesions include a broad spectrum of uncommon, benign, and aggressive, often diagnostically challenging lesions. This review aims to summarize the essential clinicopathological features of tumors of the posterior pituitary gland, infundibulum spectrum expressing thyroid transcription factor 1, and primary sellar atypical rhabdoid teratoid tumor, and provide the criteria for their diagnosis and management.
非神经内分泌肿瘤约占鞍区所有原发性肿瘤的10%。若排除脑膜瘤、颅咽管瘤和生殖细胞肿瘤,其余病变包括一系列不常见的、良性的和侵袭性的病变,这些病变往往在诊断上具有挑战性。本综述旨在总结垂体后叶肿瘤、表达甲状腺转录因子1的漏斗部病变及原发性鞍区非典型横纹肌样畸胎瘤的基本临床病理特征,并提供其诊断和治疗标准。