Anandan Ragavendiran, Lakshmi Krithika C, Ganesan Anuradha, AniyanK Yesoda
Department of Oral Medicine and Radiology, SRM Dental College, no.1 Bharathi Salai, Ramapuram, Chennai, 600089, India.
J Oral Biol Craniofac Res. 2024 Nov-Dec;14(6):669-675. doi: 10.1016/j.jobcr.2024.09.003. Epub 2024 Sep 19.
Oral submucous fibrosis (OSMF) alters the pharynx, which may affect airway size. MRI will be useful for diagnosing pharyngeal abnormalities. MRI is used to evaluate pharyngeal airway and soft palate changes in OSMF patients.
This study is a cross-sectional observational study that included a sample size of 42 patients. Group A consisted of 21 patients with OSMF, while Group B consisted of 21 volunteers without OSMF, who served as the control group. The patients with OSMF were classified into Stages I, II, and III according to the categorization established by Pindborg JJ in 1989, Stop-Bang questionnaire was employed to assess obstructive sleep apnoea. Magnetic Resonance Imaging (MRI) was utilized to acquire evaluations of the pharyngeal airway, encompassing measurements in the midsagittal, cross-sectional width, length planes, and cross-sectional area with volume, for all participants. The Shapiro-Wilk test determines distribution normality. We utilized one-way ANOVA to compare the means between groups.
The average age of OSMF patients was 45.9 ± 8.16, while the control group was 39.19 ± 4.21. Stage I of OSMF had the highest mean Stop Bang questionnaire score (2.75), followed by stage III (2.22), and stage II (1.75). Statistically significant differences (p < 0.001) were seen in volume, linear midsagittal planes, cross-sectional width and length planes, cross-sectional area, and soft palate breadth and length between OSMF and control groups.
MRI can effectively examine early changes in the pharyngeal airway of patients with OSMF thereby serving as a constructive diagnostic and motivational tool.
口腔黏膜下纤维化（OSMF）会改变咽部结构，这可能会影响气道大小。磁共振成像（MRI）有助于诊断咽部异常。MRI用于评估OSMF患者的咽气道和软腭变化。
本研究为横断面观察性研究，样本量为42例患者。A组由21例OSMF患者组成，B组由21名无OSMF的志愿者组成，作为对照组。根据Pindborg JJ于1989年制定的分类标准，将OSMF患者分为I期、II期和III期，采用阻塞性睡眠呼吸暂停综合征筛查问卷（Stop-Bang问卷）评估阻塞性睡眠呼吸暂停。利用磁共振成像（MRI）对所有参与者的咽气道进行评估，包括在矢状面、横断面宽度、长度平面以及横断面面积与体积的测量。采用夏皮罗-威尔克检验确定分布正态性。我们使用单因素方差分析比较组间均值。
OSMF患者的平均年龄为45.9±8.16岁，而对照组为39.19±4.21岁。OSMF I期的Stop Bang问卷平均得分最高（2.75），其次是III期（2.22）和II期（1.75）。OSMF组与对照组在体积、矢状面线性、横断面宽度和长度平面、横断面面积以及软腭宽度和长度方面存在统计学显著差异（p<0.001）。
MRI能够有效检测OSMF患者咽气道的早期变化，从而成为一种有建设性的诊断和评估工具。
