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来自孟加拉国医院的耐多药菌株的基因组测序数据草案。

Draft genome sequencing data of multidrug-resistant from Bangladeshi hospitals.

作者信息

Tabassum Jarin, Anjum Afia, Islam Sohidul, Khaleque Abdul, Jabeen Ishrat, Shuvo Sabbir R

机构信息

Department of Biochemistry & Microbiology, North South University, Dhaka, Bangladesh.

出版信息

Data Brief. 2024 Sep 7;57:110918. doi: 10.1016/j.dib.2024.110918. eCollection 2024 Dec.

Abstract

Here, we report the draft genome sequence data of two multidrug-resistant (MDR) strains, SAC2 and SAC7, isolated from clinical samples from Dhaka, Bangladesh. The sequence raw read files were generated using Ion Torrent Sequencing Technology using the genomic DNA from the pure culture of the strains. These two Bangladeshi strains had an average genome size of 2.49 million base pairs with a GC content of 32.6 % and an average of 1783 coding sequences. We conducted genomic studies using bioinformatics tools focusing on resistance genes, virulence factors, and toxin-antitoxin systems. A phylogenomic study with strains isolated worldwide revealed that these two Bangladeshi strains are in different nodes but clustered together. The data can be used as a starting point for understanding the genomic content, epidemiology, and evolution of in Bangladesh. The genome sequence data of SAC2 and SAC7 strains have been deposited in the NCBI database under BioSample accession numbers SAMN35731443 and SAMN35731649, respectively.

摘要

在此,我们报告了从孟加拉国达卡的临床样本中分离出的两株多重耐药(MDR)菌株SAC2和SAC7的基因组序列草图数据。序列原始读取文件是使用Ion Torrent测序技术,利用菌株纯培养物的基因组DNA生成的。这两株孟加拉国菌株的平均基因组大小为249万个碱基对,GC含量为32.6%,平均有1783个编码序列。我们使用生物信息学工具进行了基因组研究,重点关注耐药基因、毒力因子和毒素-抗毒素系统。一项对全球分离菌株的系统基因组学研究表明,这两株孟加拉国菌株处于不同节点,但聚集在一起。这些数据可作为了解孟加拉国该菌基因组内容、流行病学和进化的起点。SAC2和SAC7菌株的基因组序列数据已分别以生物样本登录号SAMN35731443和SAMN35731649存入NCBI数据库。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05cd/11440288/4e086a731250/gr1.jpg

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