Sanchez Rick F, Ledbetter Eric C, Leiva Marta
EBVS® Specialist, Dipl ECVO, DVM, CertVetEd/FHEA, Specialistische Dierenkliniek Utrecth (SDU-AniCura), Utrecht, The Netherlands.
DVM, DACVO, Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Vet Ophthalmol. 2025 Mar;28(2):519-531. doi: 10.1111/vop.13286. Epub 2024 Oct 1.
Corneal reconstruction is a key part of veterinary ophthalmic practice and numerous reconstructive techniques have been described for use in small animals in the peer-reviewed veterinary literature written in English. Despite the evidence accrued over the last six decades in over 40 clinical articles and numerous other publications on ocular surface health, several key areas require further study. The comparison between studies is difficult due to elements that go beyond common factors, such as the indication for surgery, the reconstructive technique preferred by the surgeon or the availability of reconstructive materials. However, the differences in reporting style adopted by different authors between similar studies and the lack of data found in retrospective studies add to this complexity. The present review is divided into three parts. One covers the use of autologous materials for reconstruction and corneal transplants, as well as corneal clarity. A second part focuses on biomaterials and keratoprosthetics, while the third part focuses on the use of corneal sutures and report of ocular discomfort/pain in the veterinary literature. The review focuses on the main findings of each reconstruction technique. It aims to identify areas where key information about common procedures is missing so that general guidelines may be provided for the planning of patient record keeping and future retrospective or prospective studies, while it also aims to highlight the presence of knowledge gaps that deserve further attention.
角膜重建是兽医眼科实践的关键部分,在同行评审的英文兽医文献中,已经描述了许多用于小动物的重建技术。尽管在过去六十年里,有40多篇临床文章以及众多关于眼表健康的其他出版物积累了相关证据,但仍有几个关键领域需要进一步研究。由于存在一些超出共同因素的元素,如手术适应症、外科医生偏好的重建技术或重建材料的可用性,不同研究之间的比较很困难。然而,不同作者在相似研究中采用的报告风格差异以及回顾性研究中发现的数据不足,进一步加剧了这种复杂性。本综述分为三个部分。第一部分涵盖自体材料在重建和角膜移植中的应用以及角膜透明度。第二部分聚焦生物材料和人工角膜,而第三部分则关注角膜缝线的使用以及兽医文献中关于眼部不适/疼痛的报告。该综述着重介绍了每种重建技术的主要发现。其目的是确定常见手术关键信息缺失的领域,以便为患者记录保存规划以及未来的回顾性或前瞻性研究提供通用指南,同时还旨在突出值得进一步关注的知识空白。