Maegele Marc
Klinik für Orthopädie, Unfallchirurgie und Sporttraumatologie, Klinikum Köln-Merheim, Universität Witten/Herdecke, Ostmerheimerstr. 200, 51109, Köln, Deutschland.
Institut für Forschung in der Operativen Medizin (IFOM), Campus Köln-Merheim, Universität Witten/Herdecke, Haus 38, Ostmerheimerstr. 200, 51109, Köln, Deutschland.
Radiologie (Heidelb). 2025 Jan;65(1):38-46. doi: 10.1007/s00117-024-01376-z. Epub 2024 Oct 1.
Noncompressible torso hemorrhages (NCTH) are now recognized as the leading cause of preventable death in the context of severe military and civilian injuries. Approximately 20% of all trauma patients still die from uncontrolled bleeding associated with rapidly evolving disorders of blood coagulation function.
Summary of recent advances in the field of nonsurgical and surgical management, presentation of current treatment concepts and future research directions.
Selective literature review and analysis.
The concepts for the early treatment of NCTH have considerably evolved over the last decade. The updated definition of NCTH includes a combination of high-grade anatomic body trunk injury, hemodynamic instability, urgent need for hemorrhage control, and aggressive hemostatic treatment. The treatment concepts consider the following 3 aspects: controlling the source of bleeding (close the tap), maintaining organ perfusion and restoring hemostasis (fill the tank) and increasing the body's resistance to ischemia (upgrade the armor). New tools, well-established damage control concepts and early and aggressive therapeutic intervention for hemostatic failure have significantly improved the outcomes.
Future research needs to refine and validate the current concepts for further clinical application.
不可压缩性躯干出血(NCTH)目前被认为是严重军事和民用创伤中可预防死亡的主要原因。所有创伤患者中约有20%仍死于与迅速发展的凝血功能障碍相关的失控性出血。
总结非手术和手术治疗领域的最新进展,介绍当前的治疗理念和未来的研究方向。
选择性文献回顾与分析。
在过去十年中,NCTH的早期治疗理念有了很大的发展。NCTH的更新定义包括严重的解剖学躯干损伤、血流动力学不稳定、迫切需要控制出血以及积极的止血治疗。治疗理念考虑以下三个方面:控制出血源(关上水龙头)、维持器官灌注和恢复止血(填满水箱)以及增强机体对缺血的耐受性(升级盔甲)。新工具、成熟的损伤控制理念以及对止血失败的早期积极治疗干预显著改善了治疗效果。
未来的研究需要完善和验证当前的理念,以便进一步临床应用。