Limb of Lengthening and Reconstruction Unit, Clínica Imbanaco Grupo QuirónSalud, Carrera 38A #5ª-100, Tower A, Office 803, Cali, Colombia.
Faculty of Health Sciences, Pontificia Universidad Javeriana Cali, Cali, Colombia.
Eur J Orthop Surg Traumatol. 2024 Oct;34(7):3789-3795. doi: 10.1007/s00590-024-04100-8. Epub 2024 Oct 1.
The objective of this study was to describe the use of retrograde gentamicin-coated tibial intramedullary nail (ETN PROtect™) in patients with tibial defects who required a tibiotalocalcaneal arthrodesis (TTC).
Consecutive series case review of seven men treated with TTC using retrograde PROtect™ between January 2018 and December 2023. The main outcomes evaluated were fracture union, complications, and the health-related quality of life using the EuroQol five-dimension three-level questionnaire (EQ-5D-3L).
The mean age was 45.3 8.0 years. Six patients had a clinical history of chronic osteomyelitis, and one case underwent TTC for congenital pseudoarthrosis. Fracture union was achieved in 5 of 7 patients between 4 and 11 months after surgery. Three patients developed complications; two patients had fistulas, and one had persistent pain. At the end of the follow-up, a median of 70 points (interquartile range: 60 to 90) on the EQ-5D-3L was reported. No complications directly attributed to the use of the PROtect™ were reported.
TTC with retrograde PROtect™ is a prophylactic treatment option in patients with tibial defects treated with external fixation requiring a tibiotalar and subtalar arthrodesis. This novel use of PROtect™ allows simultaneous fixation of the tibiotalocalcaneal joint and protection of the regenerated bone, facilitating earlier rehabilitation in patients at high risk for postoperative infections.
本研究旨在描述在需要行胫距跟关节融合术(TTC)的胫骨缺损患者中使用逆行顺行抗生素涂层胫骨髓内钉(ETN PROtect™)的情况。
对 2018 年 1 月至 2023 年 12 月期间使用逆行 PROtect™行 TTC 的 7 例男性患者进行连续系列病例回顾。主要评估的结果包括骨折愈合、并发症和使用欧洲五维健康量表 3 级问卷(EQ-5D-3L)评估的健康相关生活质量。
平均年龄为 45.3 ± 8.0 岁。6 例患者有慢性骨髓炎的临床病史,1 例患者因先天性假关节行 TTC。5 例患者在术后 4 至 11 个月实现骨折愈合。3 例患者出现并发症;2 例患者有瘘管,1 例患者有持续性疼痛。在随访结束时,EQ-5D-3L 的中位数为 70 分(四分位距:60 至 90)。未报告与 PROtect™使用直接相关的并发症。
对于需要行外固定架固定且需要行胫距和距下关节融合术的胫骨缺损患者,逆行 PROtect™TTC 是一种预防性治疗选择。PROtect™的这种新用途可同时固定胫距跟关节并保护再生骨,便于对术后感染风险高的患者进行早期康复。