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Octopamine reduces potassium permeability of the glia that form the insect blood-brain barrier.

作者信息

Schofield P K, Treherne J E

出版信息

Brain Res. 1985 Dec 23;360(1-2):344-8. doi: 10.1016/0006-8993(85)91252-1.

DOI:10.1016/0006-8993(85)91252-1
PMID:3935276
Abstract

Octopamine caused only a slight reduction in the potential across the perineurial glia of the cockroach, had no effect upon sodium-induced changes in potential, but did reduce potassium-induced changes (at 10(-7) M and above). The effect of 10(-7) M octopamine was accompanied by a rise in resistance, was mimicked by 10(-7) M synephrine and blocked by 10(-6) M phentolamine. Transperineurial potassium permeability was reduced by 10(-6) M octopamine. It is concluded that octopamine receptors mediate a reduction in potassium conductance of the basolateral membrane of these glia, and a reduction in the net potassium permeability of the barrier.

摘要

相似文献

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