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菱形肋间神经阻滞在胸外科和乳腺外科术后镇痛中的疗效和安全性:系统评价和荟萃分析。

The Efficacy and Safety of the Rhomboid Intercostal Block for Postoperative Analgesia in Chest Surgery and Breast Surgery: A Systemic Review and Meta-Analysis.

机构信息

Department of Anesthesiology, Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China.

出版信息

Pain Physician. 2024 Sep;27(7):375-385.

Abstract

BACKGROUND

Prior research has suggested that the rhomboid intercostal block (RIB) may contribute to postoperative analgesia after surgeries of the chest and breast.

OBJECTIVE

To explore the effectiveness and safety of RIB for postoperative analgesia, as well as whether RIB is superior to other types of nerve blocks.

STUDY DESIGN

A systematic review and meta-analysis.

SETTING

Querying electronic databases, including the Cochrane Library, PubMed, Embase, and Web of Science, was part of the process in searching for eligible clinical trials for this meta-analysis and systematic review.

METHODS

The Cochrane Collaboration's tool for quality evaluation was utilized in assessing the bias risk in the selected randomized controlled trials (RCTs). meta-analysis was facilitated through the utilization of Review Manager 5.3. The determination of the evidence's quality adhered to the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach.

RESULTS

After the inclusion and exclusion criteria were established, the incorporation of 8 RCTs, encompassing 714 patients, took place. During the first 24 hours after the operation, patients in the RIB group exhibited lower pain scores and less opioid consumption than did those in the no-block group. Furthermore, a decrease in the incidence of postoperative vomiting and nausea was noted in the RIB group. Nevertheless, when comparing outcomes, it was revealed that the RIB group and the other nerve block group did not differ significantly.

LIMITATIONS

No subgroup analysis to investigate the sources of heterogeneity was performed. The number of studies in this meta-analysis of RIB compared to those that focus on other types of nerve block is relatively small. The optimal concentrations and volumes of local anesthetics were not evaluated.

CONCLUSIONS

RIB may be a new option for pain relief after chest and breast surgery.

摘要

背景

先前的研究表明,菱形肋间阻滞(RIB)可能有助于胸部和乳房手术后的术后镇痛。

目的

探索 RIB 用于术后镇痛的有效性和安全性,以及 RIB 是否优于其他类型的神经阻滞。

研究设计

系统评价和荟萃分析。

设置

在本荟萃分析和系统评价中,查询电子数据库,包括 Cochrane 图书馆、PubMed、Embase 和 Web of Science,以寻找合格的临床试验。

方法

使用 Cochrane 协作工具评估偏倚风险对入选的随机对照试验(RCT)进行质量评估。通过使用 Review Manager 5.3 进行荟萃分析。证据质量的确定遵循推荐评估、制定和评估(GRADE)方法。

结果

在确定纳入和排除标准后,纳入了 8 项 RCT,共纳入 714 名患者。在手术后的 24 小时内,RIB 组患者的疼痛评分和阿片类药物消耗量均低于无阻滞组。此外,RIB 组患者术后呕吐和恶心的发生率降低。然而,当比较结果时,发现 RIB 组和其他神经阻滞组之间没有显著差异。

局限性

未进行亚组分析以探讨异质性的来源。与其他类型的神经阻滞相比,本 RIB 荟萃分析中的研究数量相对较少。未评估局部麻醉剂的最佳浓度和体积。

结论

RIB 可能是胸部和乳房手术后缓解疼痛的一种新选择。

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