Department of Anesthesiology and Reanimation, Etlik City Hospital, Ankara, Turkey.
J Anesth. 2024 Oct;38(5):584-590. doi: 10.1007/s00540-024-03351-3. Epub 2024 May 22.
The objective of this study was to examine the hypothesis that the opioid consumption of patients who receive a rhomboid intercostal block (RIB) or a pectoral nerve (PECS) block after unilateral modified radical mastectomy (MRM) surgery is less than that of patients who receive local anesthetic infiltration.
Eighty-one female patients aged 18-70 years who underwent unilateral MRM surgery with general anesthesia were randomly allocated to three groups. The first group received an RIB with 30 ml of 0.25% bupivacaine on completion of the surgery, and the second received a PECS block with the same volume and concentration of local anesthetic. In the third (control) group, local infiltration was applied to the wound site with 30 ml of 0.25% bupivacaine at the end of the surgery. The patients' total tramadol consumption, quality of recovery (QoR), postoperative pain scores, and sleep quality were evaluated in the first 24 h postoperatively.
Both the RIB (58.3 ± 22.8 mg) and PECS (68.3 ± 21.2 mg) groups had significantly lower tramadol consumption compared to the control group (92.5 ± 25.6 mg) (p < 0.001 and p = 0.002, respectively). Higher QoR scores were observed in the RIB and PECS groups than the control group at 6 h post-surgery. The lowest pain values were observed in the RIB group. The sleep quality of the patients in the RIB and PECS groups was better than that of the control group (p < 0.001).
Compared to local anesthetic infiltration, the RIB and PECS blocks applied as part of multimodal analgesia in MRM surgery reduced opioid consumption in the first 24 h and improved the quality of recovery in the early period.
本研究旨在检验以下假设,即接受菱形肋间阻滞(RIB)或胸长神经(PECS)阻滞的单侧改良根治性乳房切除术(MRM)术后患者的阿片类药物消耗量低于接受局部麻醉浸润的患者。
81 名年龄在 18-70 岁之间的女性患者接受全身麻醉下的单侧 MRM 手术,随机分为三组。第一组在手术完成时接受 30ml 0.25%布比卡因的 RIB,第二组接受相同体积和浓度的局部麻醉的 PECS 阻滞。在第三(对照组)组中,在手术结束时在伤口部位应用 30ml 0.25%布比卡因进行局部浸润。术后 24 小时内评估患者的曲马多总消耗量、恢复质量(QoR)、术后疼痛评分和睡眠质量。
RIB(58.3±22.8mg)和 PECS(68.3±21.2mg)组的曲马多消耗量均明显低于对照组(92.5±25.6mg)(p<0.001 和 p=0.002)。与对照组相比,RIB 和 PECS 组在术后 6 小时时的 QoR 评分更高。RIB 组的疼痛值最低。RIB 和 PECS 组的患者睡眠质量优于对照组(p<0.001)。
与局部麻醉浸润相比,RIB 和 PECS 阻滞作为 MRM 手术多模式镇痛的一部分,可减少术后 24 小时内阿片类药物的消耗,并在早期改善恢复质量。