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用于治疗肠癌的中草药:临床前研究及潜在临床应用

Chinese herbal medicine for the treatment of intestinal cancer: preclinical studies and potential clinical applications.

作者信息

Zhang Juan, Wu Yulin, Tian Yuanyang, Xu Hongxi, Lin Zhi-Xiu, Xian Yan-Fang

机构信息

School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, 999077, N.T., Hong Kong SAR, China.

School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, P.R. China.

出版信息

Mol Cancer. 2024 Oct 1;23(1):217. doi: 10.1186/s12943-024-02135-3.

Abstract

Intestinal cancer (IC) poses a significant global health challenge that drives continuous efforts to explore effective treatment modalities. Conventional treatments for IC are effective, but are associated with several limitations and drawbacks. Chinese herbal medicine (CHM) plays an important role in the overall cancer prevention and therapeutic strategies. Recent years have seen a growing body of research focus on the potential of CHM in IC treatment, showing promising results in managing IC and mitigating the adverse effects of radiotherapy and chemotherapy. This review provides updated information from preclinical research and clinical observation on CHM's role in treatment of IC, offering insights into its comprehensive management and guiding future prevention strategies and clinical practice.

摘要

肠癌对全球健康构成了重大挑战,促使人们不断努力探索有效的治疗方式。肠癌的传统治疗方法虽有疗效,但存在一些局限性和缺点。中药在整体癌症预防和治疗策略中发挥着重要作用。近年来,越来越多的研究聚焦于中药在肠癌治疗中的潜力,在治疗肠癌以及减轻放疗和化疗的不良反应方面显示出了有前景的结果。本综述提供了来自临床前研究和临床观察的关于中药在肠癌治疗中作用的最新信息,为其综合管理提供见解,并指导未来的预防策略和临床实践。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b606/11443726/35b00dc700b6/12943_2024_2135_Fig1_HTML.jpg

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