Wang Mingyao, Yang Xiao, Wang Mengyue, He Yunxiang, Huang Tao, Wang Xiaoling, Yang Qichang, Guo Junling
BMI Center for Biomass Materials and Nanointerfaces, College of Biomass Science and Engineering, Sichuan University, Chengdu, Sichuan, 610065, China.
Institute of Urban Agriculture, Chinese Academy of Agricultural Sciences (IUA-CAAS), Chengdu National Agricultural Science and Technology Center, Chengdu, Sichuan, 610213, China.
Chemistry. 2024 Dec 18;30(71):e202403035. doi: 10.1002/chem.202403035. Epub 2024 Nov 5.
Achieving food sustainability is one of the biggest challenges in the new millennium. Plant factory cultivation systems provide an alternative for food sustainability, while they often suffer from algal blooms. The overuse of conventional algaecides has caused significant environmental pollution and concerns about food security. Here, we design a nanoenabled metal-organic algaecide that is self-assembled from natural polyphenols and two functional metal ions for providing shading effects and delivering active ingredients synergistically to suppress algal blooms. Black wattle tannin (BWT) and Fe ions are utilized to develop self-assembled FeBWT nanoalgaecides with significant shading effects for decreasing light transmission (up to 97 %) and effectively inhibiting algal photosynthesis. Further, the FeBWT is functionalized with Cu ions (bimetallic Cu/FeBWT) to target the algal cells and release Cu ions via phenolic-mediated cell surface interactions, thus enhancing the inhibition efficiency. Importantly, the biosafety of Cu/FeBWT is demonstrated through toxicity tests on zebrafish and NIH3T3 cells. In our real-world field test, the Cu/FeBWT demonstrates high algal inhibition performance (>95 %, over 30 days), and enhances the accumulation of food nutrients in model plant lettuces. Collectively, the supramolecular metal-organic nanoalgaecide provides a promise for nanoagrochemical application and promotes food sustainability and security.
实现粮食可持续性是新千年面临的最大挑战之一。植物工厂栽培系统为粮食可持续性提供了一种替代方案，但它们经常遭受藻华问题。传统杀藻剂的过度使用已造成严重的环境污染并引发对食品安全的担忧。在此，我们设计了一种由天然多酚和两种功能金属离子自组装而成的纳米金属有机杀藻剂，用于提供遮光效果并协同递送活性成分以抑制藻华。利用黑荆树单宁（BWT）和铁离子开发出自组装的FeBWT纳米杀藻剂，其具有显著的遮光效果，可降低光透射率（高达97%）并有效抑制藻类光合作用。此外，用铜离子对FeBWT进行功能化（双金属Cu/FeBWT），以靶向藻类细胞并通过酚介导的细胞表面相互作用释放铜离子，从而提高抑制效率。重要的是，通过对斑马鱼和NIH3T3细胞的毒性测试证明了Cu/FeBWT的生物安全性。在我们的实际田间试验中，Cu/FeBWT表现出高藻类抑制性能（>95%，超过30天），并提高了模式植物生菜中食物营养成分的积累。总的来说，这种超分子金属有机纳米杀藻剂为纳米农用化学品的应用带来了希望，并促进了粮食可持续性和安全性。
