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极度肥胖患者肥胖低通气综合征的管理:一项病例研究。

Management of Obesity Hypoventilation Syndrome in Extreme Obesity: A Case Study.

作者信息

Miyoshi Yuya, Yumoto Tetsuya, Kosaki Yoshinori, Hongo Takashi, Tsukahara Kohei, Nakao Atsunori, Naito Hiromichi

机构信息

Department of Emergency, Critical Care, and Disaster Medicine, Faculty of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University, Okayama, Japan.

出版信息

Am J Case Rep. 2024 Oct 2;25:e945112. doi: 10.12659/AJCR.945112.

DOI:10.12659/AJCR.945112
PMID:39354710
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11460406/
Abstract

BACKGROUND Obesity hypoventilation syndrome (OHS) is characterized by hypercapnia in obese patients, with acute hypercapnic respiratory failure often worsened by various conditions. Managing super-super obese patients presents complex challenges in critical care. Our case report details the successful treatment of acute respiratory failure in a patient with a body mass index (BMI) over 80 kg/m², highlighting the importance of comprehensive, multidisciplinary care in the Intensive Care Init (ICU). CASE REPORT A 39-year-old man with a BMI of 81.1 kg/m² presented to our emergency department with respiratory distress, altered consciousness, and an inability to move independently. Arterial blood gas analysis revealed severe hypercapnia and hypoxemia, indicating decompensated OHS. Laboratory tests and computed tomography scans suggested his condition was exacerbated by pneumonia and congestive heart failure. The patient was managed in the ICU with endotracheal intubation, mechanical ventilation, and esophageal pressure monitoring. In addition to antibiotics, diuretics were used to manage fluid balance. His care included multidisciplinary support with nutritional management and active physiotherapy. After 15 days, he was weaned from the ventilator and discharged from the ICU on day 20, continuing rehabilitation until he was discharged home on day 60. CONCLUSIONS This case report describes the successful treatment of acute hypercapnic respiratory failure from decompensated OHS in a super-super obese patient. Addressing the underlying conditions and tailoring clinical practices to the patient's specific needs, especially regarding ventilatory support, fluid balance, and nutrition, were crucial. A collaborative multidisciplinary approach was essential for improving outcomes.

摘要

背景

肥胖低通气综合征(OHS)的特征是肥胖患者出现高碳酸血症,各种情况常使急性高碳酸血症呼吸衰竭加重。在重症监护中,管理极度肥胖患者面临复杂挑战。我们的病例报告详细介绍了一名体重指数(BMI)超过80kg/m²的患者急性呼吸衰竭的成功治疗,突出了重症监护病房(ICU)综合多学科护理的重要性。

病例报告

一名39岁男性,BMI为81.1kg/m²,因呼吸窘迫、意识改变和无法独立活动就诊于我院急诊科。动脉血气分析显示严重高碳酸血症和低氧血症,提示OHS失代偿。实验室检查和计算机断层扫描显示,肺炎和充血性心力衰竭使他的病情加重。该患者在ICU接受气管插管、机械通气和食管压力监测治疗。除使用抗生素外,还使用利尿剂来维持液体平衡。他的护理包括营养管理和积极物理治疗的多学科支持。15天后,他脱机,在第20天从ICU出院,继续康复治疗,直到第60天出院回家。

结论

本病例报告描述了一名极度肥胖患者失代偿性OHS所致急性高碳酸血症呼吸衰竭的成功治疗。解决潜在疾病并根据患者的具体需求调整临床实践,特别是在通气支持、液体平衡和营养方面,至关重要。协作的多学科方法对于改善治疗结果至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8c9/11460406/c3255dafbb07/amjcaserep-25-e945112-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8c9/11460406/81ce76111de8/amjcaserep-25-e945112-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8c9/11460406/517c27d67b58/amjcaserep-25-e945112-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8c9/11460406/c3255dafbb07/amjcaserep-25-e945112-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8c9/11460406/81ce76111de8/amjcaserep-25-e945112-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8c9/11460406/517c27d67b58/amjcaserep-25-e945112-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8c9/11460406/c3255dafbb07/amjcaserep-25-e945112-g003.jpg

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