Pathivada Lumbini, Kapur Dhani, Pandranki Jayalakshmi, Krishna Karthik M, Kajapuram Prem K, Kumar Brij
Department of Paediatric and Preventive Dentistry, Rungta College of Dental Sciences and Research, Bhilai, Chhattisgarh, India.
Department of Paedodontics and Preventive Dentistry, GITAM Dental College and Hospital, Visakhapatnam, Andhra Pradesh, India.
Int J Clin Pediatr Dent. 2024 May;17(5):511-517. doi: 10.5005/jp-journals-10005-2725.
To evaluate the reduction of microbial loading using , , and as irrigating agents in deciduous molars after pulpectomy.
A controlled, randomized clinical trial involving 150 multirooted deciduous molars from both genders between 6 and 9 years old children were included, 30 molars irrigated with (group I), Triphala (group II), (group III), chlorhexidine (CHX) (group IV), and saline (group V) each. In all cases, two microbiological samples from within the canal were taken with sterile paper points, one before the first irrigation and the other immediately after pulp extirpation. Cleaning and shaping were completed with intermittent irrigation with 10 mL of experimental irrigants in the initial visit. After 3 days, reentry to the root canal was obtained, rinsed with 5 mL of the test irrigants, and the second microbial sample was collected. All the microbial samples obtained were cultured under anaerobic conditions on blood agar. The colony-forming units (CFUs) were counted using a colony counter. Data was analyzed using paired student -test and Tukey's test.
After analysis of the pre- and postsamples in all groups, a strong significant decrease in bacterial load ( ≤ 0.001) was found with CHX, , and Triphala.
and , with effective antimicrobial efficacy, can be suggested as an alternative root canal irrigant as CHX, while was found ineffective in reducing microbial count as normal saline.
Pathivada L, Kapur D, Pandranki J, Comparison of Antimicrobial Efficacy of , Triphala, and Extracts as Root Canal Irrigants in Primary Molars: A Randomized Clinical Trial. Int J Clin Pediatr Dent 2024;17(5):511-517.
评估在乳牙牙髓摘除术后使用[具体物质1]、[具体物质2]和[具体物质3]作为冲洗剂对微生物负荷的降低情况。
纳入一项对照随机临床试验，涉及6至9岁儿童的150颗多根乳牙，每组30颗磨牙，分别用[具体物质1]（第一组）、三果汤（第二组）、[具体物质3]（第三组）、氯己定（CHX）（第四组）和生理盐水（第五组）进行冲洗。在所有病例中，用无菌纸尖从根管内采集两份微生物样本，一份在首次冲洗前，另一份在牙髓摘除后立即采集。在初次就诊时，用10 mL实验冲洗剂进行间歇性冲洗以完成根管清理和成形。3天后，再次进入根管，用5 mL测试冲洗剂冲洗，并采集第二份微生物样本。所有获得的微生物样本在血琼脂上厌氧培养。使用菌落计数器计算菌落形成单位（CFU）。数据采用配对学生t检验和Tukey检验进行分析。
对所有组的术前和术后样本进行分析后发现，CHX、[具体物质1]和三果汤使细菌负荷显著大幅降低（P≤0.001）。
[具体物质1]和三果汤具有有效的抗菌效果，可作为CHX的替代根管冲洗剂，而[具体物质3]在降低微生物数量方面与生理盐水一样无效。
Pathivada L, Kapur D, Pandranki J, [具体物质1]、三果汤和[具体物质3]提取物作为乳牙根管冲洗剂的抗菌效果比较：一项随机临床试验。《国际临床儿科牙科学杂志》2024；17(5):511 - 517。
