Podar Rajesh, Kulkarni Gaurav P, Dadu Shifali S, Singh Shraddha, Singh Shishir H
Department of Conservative Dentistry and Endodontics, Terna Dental College, Nerul, Navi Mumbai, Maharashtra, India.
Eur J Dent. 2015 Oct-Dec;9(4):529-534. doi: 10.4103/1305-7456.172615.
To evaluate and compare the antimicrobial efficacy of 6% Morinda citrifolia, Azadirachta indica, and 3% sodium hypochlorite (NaOCl) as root canal irrigants.
Thirty nonvital maxillary anteriors were randomly assigned to one of the three groups corresponding to the irrigant to be tested; 6% Morinda citrifolia juice (MCJ) (n = 10), A. indica (n = 10) and 3% NaOCl (n = 10). After the root canal access opening a root canal culture sample was taken with two paper points and cultured under aerobic and anaerobic conditions. Cleaning and shaping were completed with irrigation by 10 mL of respective irrigants and 5 mL of final rinse. The patients were recalled after 3 days and canals were rinsed again with 5 mL of the test irrigants. This was followed by obtaining a posttreatment root canal culture sample and culturing and analyzed by counting the colony forming units (CFUs).
Six percentage MCJ, A. indica, and 3% NaOCl showed a significant reduction (P < 0.05) in the mean CFU counts for aerobic and anaerobic bacteria between baseline and 3 days.
There was no difference in the antimicrobial efficacy of 6% M. citrifolia, A. indica, and 3% NaOCl as root canal irrigants.
评估并比较6%海巴戟、印楝以及3%次氯酸钠（NaOCl）作为根管冲洗剂的抗菌效果。
将30颗无活力的上颌前牙随机分为三组，分别对应要测试的冲洗剂；6%海巴戟汁（MCJ）（n = 10）、印楝（n = 10）和3%次氯酸钠（n = 10）。在开髓后，用两根纸尖获取根管培养样本，并在需氧和厌氧条件下培养。用10 mL相应冲洗剂冲洗并进行根管清理和成形，最后用5 mL冲洗剂冲洗。3天后召回患者，再次用5 mL测试冲洗剂冲洗根管。随后获取根管治疗后的培养样本，通过计算菌落形成单位（CFU）进行培养和分析。
6% MCJ、印楝和3% NaOCl在基线和3天时，需氧菌和厌氧菌的平均CFU计数均显著降低（P < 0.05）。
6%海巴戟、印楝和3% NaOCl作为根管冲洗剂的抗菌效果无差异。
