Sun Yao, Zhao Huiying, An Youzhong
Department of Critical Care Medicine, Peking University People's Hospital, Beijing, People's Republic of China.
Int Med Case Rep J. 2024 Sep 27;17:809-817. doi: 10.2147/IMCRJ.S462543. eCollection 2024.
Guillain-Barré syndrome (GBS) stands out as the most prevalent and severe acute immune-mediated paralytic neuropathy. Approximately 30% of patients experience respiratory failure necessitating admission to the intensive care unit (ICU) and invasive mechanical ventilation. The management of diseases concomitant with acute respiratory distress syndrome (ARDS) poses significant challenges. This case report illustrates the swift development of ARDS in a patient with GBS, explores the utility of the biomarker neurofilament light chain, and highlights the unexpected advantages of proactive ARDS intervention.
吉兰-巴雷综合征(GBS)是最常见且最严重的急性免疫介导性麻痹性神经病。约30%的患者会出现呼吸衰竭,需要入住重症监护病房(ICU)并接受有创机械通气。合并急性呼吸窘迫综合征(ARDS)疾病的管理带来了重大挑战。本病例报告阐述了1例GBS患者中ARDS的迅速发展,探讨了生物标志物神经丝轻链的效用,并强调了积极干预ARDS的意外益处。