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一名慢性淋巴细胞白血病合并浆细胞瘤患者的诊断与管理

Diagnosis and Management of a Patient With Chronic Lymphocytic Leukemia and a Concurrent Plasmacytoma.

作者信息

Thor Danielle C, Umrani Rohan, Bergal Jack, Yang Charles, Gordon Richard

机构信息

Department of Internal Medicine Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

出版信息

Case Rep Oncol Med. 2024 Sep 24;2024:8870681. doi: 10.1155/2024/8870681. eCollection 2024.

Abstract

Chronic lymphocytic leukemia (CLL) typically presents as an indolent disease with a benign disposition in most patients. In select patients, CLL can progress into a more aggressive disease via its original morphology, following a Richter transformation to an alternative non-Hodgkin's lymphoma, or with the concomitant development of multiple myeloma. In an extremely rare subset of individuals with CLL, an extramedullary plasmacytoma may coexist. This case report seeks to describe the diagnosis and treatment of a patient with concurrent CLL and a plasmacytoma.

摘要

慢性淋巴细胞白血病(CLL)在大多数患者中通常表现为一种惰性疾病,具有良性病程。在部分患者中,CLL可通过其原始形态进展为侵袭性更强的疾病,发生里氏转化成为另一种非霍奇金淋巴瘤,或同时合并多发性骨髓瘤。在CLL患者的一个极其罕见的亚组中,可能并存髓外浆细胞瘤。本病例报告旨在描述一名同时患有CLL和浆细胞瘤患者的诊断和治疗情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5918/11444798/37c0fc343c44/CRIONM2024-8870681.001.jpg

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