排便障碍与抑郁症状之间的关联：一项横断面研究。
Association between bowel movement disorders and depressive symptoms: a cross-sectional study.
作者信息
Wang Linyue, Tian Maosheng, Sun Hongyuan, Gao Jihua, Qi Wenyue, Xu Jiancheng, An Yongkang, Xu Wencong
机构信息
Graduate School, Hebei University of Chinese Medicine, Shijiazhuang, China.
Anorectal Surgery Department, The First Affiliated Hospital of Hebei University of Chinese Medicine, Shijiazhuang, China.
出版信息
Front Psychiatry. 2024 Sep 17;15:1449948. doi: 10.3389/fpsyt.2024.1449948. eCollection 2024.
OBJECTIVES
This study aimed to explore the association between bowel movement disorders and depression in adults.
METHOD
A cross-sectional study was conducted using data from the National Health and Nutritional Examination Survey (NHANES), 2005-2010. Depression, constipation, diarrhea, and fecal incontinence were self-reported via questionnaires. Weighted logistic regression and subgroup analyses were performed to explore the association between bowel movement disorders and the risk of depression. Restricted cubic spline (RCS) was also conducted to investigate the association between bowel movements disorder and depression.
RESULTS
A total of 13,820 participants were collected. Compared to the participants with normal bowel movements, the full-adjusted depression model ORs for constipation and diarrhea were 2.28 (95%CI,1.78-2.92), 1.75 (95%CI,1.31-2.31), respectively. Any kind of bowel leakage were associated with depression. The RCS showed the possible nonlinear association between bowel movement frequency/stool shape and depression.
CONCLUSIONS
Constipation, diarrhea, and bowel leakage are associated with an increased risk of depression.
目的
本研究旨在探讨成人排便障碍与抑郁症之间的关联。
方法
采用2005 - 2010年美国国家健康与营养检查调查（NHANES）的数据进行横断面研究。通过问卷调查自我报告抑郁症、便秘、腹泻和大便失禁情况。进行加权逻辑回归和亚组分析以探讨排便障碍与抑郁症风险之间的关联。还采用受限立方样条（RCS）来研究排便障碍与抑郁症之间的关联。
结果
共收集了13820名参与者。与排便正常的参与者相比，便秘和腹泻的完全调整抑郁症模型的比值比分别为2.28（95%置信区间，1.78 - 2.92）和1.75（95%置信区间，1.31 - 2.31）。任何类型的大便失禁都与抑郁症有关。RCS显示排便频率/大便形状与抑郁症之间可能存在非线性关联。
结论
便秘、腹泻和大便失禁与抑郁症风险增加有关。
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