BluePearl Pet Hospital, 11950 W. 110th Street, Overland Park, Kansas 66210, USA (Buchanan, Thomason); Department of Clinical Sciences, Kansas State University, 1800 Denison Avenue, Manhattan, Kansas 66506, USA (Lynn, Hallman).
Can Vet J. 2024 Oct;65(10):1028-1033.
This case series describes spontaneous resolution of systolic anterior motion of the mitral valve, cessation of a dynamic left ventricular outflow tract obstruction, and reverse cardiac remodeling in 4 young cats. Following initial presentation with or without congestive heart failure, subsequent rechecks documented resolution of systolic anterior motion of the mitral valve and normalization of left heart dimensions. Those cats originally presented with congestive heart failure were successfully weaned off diuretic medications. Atenolol was prescribed to all 4 cats, and all remained on oral atenolol through the final recheck. There was no documented recurrence of progressive heart disease and heart failure in any of the cats. Consideration is given to transient myocardial thickening, spontaneous resolution of mitral valve dysplasia, and response to beta-1 adrenergic antagonism as possible underlying mechanisms. Key clinical message: When presented with young cats with hypertrophic obstructive cardiomyopathy, veterinarians should consider multiple differential diagnoses, as lifespan in these cases may be longer than typically expected for cats with primary hypertrophic cardiomyopathy, even with concurrent congestive heart failure.
本病例系列描述了 4 只年轻猫自发性二尖瓣收缩前运动消退、左心室流出道动态梗阻停止和心脏逆重构。最初表现为充血性心力衰竭或无充血性心力衰竭，随后的复查显示二尖瓣收缩前运动消退，左心腔尺寸正常。最初表现为充血性心力衰竭的猫成功地停用了利尿剂。所有 4 只猫均被开具了阿替洛尔，所有猫在最后一次复查时仍在口服阿替洛尔。这些猫均无进行性心脏病和心力衰竭复发的记录。考虑可能存在短暂性心肌肥厚、二尖瓣发育不良的自发性消退和对β-1 肾上腺素能拮抗剂的反应等潜在机制。关键临床信息：当遇到患有肥厚型梗阻性心肌病的年轻猫时，兽医应考虑多种鉴别诊断，因为这些猫的寿命可能比原发性肥厚型心肌病猫通常预期的寿命更长，即使同时伴有充血性心力衰竭。
