• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

非阳光暴露部位的巨大基底细胞癌:四年随访病例报告

Giant basal cell carcinoma in a non-sun exposed area with four years follow-up: a case report.

作者信息

Alhetheli Ghadah

机构信息

Department of Dermatology and Cutaneous Surgery, College of Medicine, Qassim University, Buraidah, Saudi Arabia.

出版信息

Pan Afr Med J. 2024 Jun 27;48:70. doi: 10.11604/pamj.2024.48.70.44097. eCollection 2024.

DOI:10.11604/pamj.2024.48.70.44097
PMID:39355711
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11444085/
Abstract

Basal cell carcinoma (BCC) is a low-grade malignant tumor that if properly managed has an excellent prognosis. Development of BCC outside the skin areas exposed to sun rays is infrequent. Giant BCC is a rare entity, especially in unexposed areas of the body. It carries a considerable implication on patients' quality of life because of the risk of being a source of infection that may progress to severe sepsis and/or metastasis. An old female presented with a long-standing solitary lesion measuring 7.5x6 cm overlaying the lumber 4-5 vertebral region about 2.5 cm from the line of the sacral promontory. No lymph nodes or distant metastases were detected. For many years, it was misdiagnosed by other physicians as eczema, psoriasis, and fungal infection and accordingly failed to respond to treatment. A histopathological examination of lesional punch biopsy assured the diagnosis of giant superficially spreading BCC. The lesion was excised with a circumferential safety margin of about 5 mm. During the follow-up period of 4 years, no recurrence was detected. Despite being a long-standing Giant basal cell carcinoma (GBCC) in a sun-hidden skin area, the growth behaved as a locally malignant lesion without metastasizing. A wide local surgical excision of the GBCC with 5 mm safety margins was feasible, safe, and with a good aesthetic outcome. Importantly, family practitioners should avoid such missed cases through accuracy in their diagnosis and early referral of any atypical cases to a dermatologist.

摘要

基底细胞癌(BCC)是一种低级别恶性肿瘤,若得到妥善处理,预后良好。在未暴露于阳光的皮肤区域发生BCC的情况并不常见。巨大基底细胞癌是一种罕见的病症,尤其是在身体未暴露部位。由于存在感染风险,可能进展为严重脓毒症和/或转移,这对患者的生活质量有相当大的影响。一名老年女性患者,在第4 - 5腰椎区域距骶岬连线约2.5厘米处有一个长期存在的孤立性病灶,大小为7.5×6厘米。未检测到淋巴结或远处转移。多年来,其他医生一直将其误诊为湿疹、银屑病和真菌感染,因此治疗无效。对病灶进行打孔活检的组织病理学检查确诊为巨大浅表扩散型BCC。该病灶以约5毫米的周缘安全切缘切除。在4年的随访期内,未检测到复发。尽管这是一个位于阳光照射不到的皮肤区域的长期巨大基底细胞癌(GBCC),但其生长表现为局部恶性病变,未发生转移。对GBCC进行带5毫米安全切缘的广泛局部手术切除是可行、安全的,且美容效果良好。重要的是,家庭医生应通过准确诊断并将任何非典型病例尽早转诊给皮肤科医生,避免出现此类漏诊情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3564/11444085/df8a979fd876/PAMJ-48-70-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3564/11444085/0cb4763ddce0/PAMJ-48-70-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3564/11444085/322fdd12c3a2/PAMJ-48-70-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3564/11444085/df8a979fd876/PAMJ-48-70-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3564/11444085/0cb4763ddce0/PAMJ-48-70-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3564/11444085/322fdd12c3a2/PAMJ-48-70-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3564/11444085/df8a979fd876/PAMJ-48-70-g003.jpg

相似文献

1
Giant basal cell carcinoma in a non-sun exposed area with four years follow-up: a case report.非阳光暴露部位的巨大基底细胞癌:四年随访病例报告
Pan Afr Med J. 2024 Jun 27;48:70. doi: 10.11604/pamj.2024.48.70.44097. eCollection 2024.
2
Surgical management of giant skin tumor - A case report.巨大皮肤肿瘤的外科治疗——病例报告。
Ann Chir Plast Esthet. 2024 Mar;69(2):154-159. doi: 10.1016/j.anplas.2023.06.010. Epub 2023 Jul 7.
3
A Giant Basal Cell Carcinoma Misdiagnosed and Mistreated as a Chronic Venous Ulcer.一例被误诊误治为慢性静脉溃疡的巨大基底细胞癌
Acta Dermatovenerol Croat. 2016 Dec;24(4):296-298.
4
Implication of wide surgical excision in minimizing positive margins and consequential secondary excision - a retrospective comparative study involving 106 basal cell carcinoma cases.广泛手术切除对减少阳性切缘和随后的二次切除的意义——一项涉及 106 例基底细胞癌病例的回顾性对比研究。
Eur Rev Med Pharmacol Sci. 2021 Jun;25(12):4283-4288. doi: 10.26355/eurrev_202106_26134.
5
Diagnostic accuracy of autofluorescence-Raman microspectroscopy for surgical margin assessment during Mohs micrographic surgery of basal cell carcinoma.自动荧光拉曼微光谱技术在基底细胞癌 Mohs 显微外科手术中评估手术切缘的诊断准确性。
Br J Dermatol. 2024 Aug 14;191(3):428-436. doi: 10.1093/bjd/ljae196.
6
Exfoliative cytology for diagnosing basal cell carcinoma and other skin cancers in adults.用于诊断成人基底细胞癌和其他皮肤癌的脱落细胞学检查。
Cochrane Database Syst Rev. 2018 Dec 4;12(12):CD013187. doi: 10.1002/14651858.CD013187.
7
Giant superficial basal cell carcinoma of the scrotum.阴囊巨大浅表性基底细胞癌。
Eur J Dermatol. 2005 May-Jun;15(3):186-8.
8
A Rare Case of Giant Basal Cell Carcinoma of the Abdominal Wall: Excision and Immediate Reconstruction with a Pedicled Deep Inferior Epigastric Artery Perforator (DIEP) Flap.腹壁巨大基底细胞癌罕见病例:采用带蒂腹壁下动脉穿支(DIEP)皮瓣切除并即刻重建
Am J Case Rep. 2017 Dec 4;18:1284-1288. doi: 10.12659/ajcr.905671.
9
Giant polypoid basal cell carcinoma with features of fibroepithelioma of Pinkus and extensive cornification.具有平卡斯纤维上皮瘤特征及广泛角化的巨大息肉状基底细胞癌。
Eur J Dermatol. 2004 Jul-Aug;14(4):272-5.
10
A retrospective study of 694 Basal Cell Carcinoma excisions to quantify deep margin documentation and clearance compared to histological type and surgical margin.一项对694例基底细胞癌切除术的回顾性研究,旨在量化与组织学类型和手术切缘相关的深部切缘记录及切缘情况。
J Plast Reconstr Aesthet Surg. 2019 Nov;72(11):1805-1812. doi: 10.1016/j.bjps.2019.06.002. Epub 2019 Jun 27.

本文引用的文献

1
Patient-dependent risk factors for wound infection after skin surgery: A systematic review and meta-analysis.患者相关的皮肤手术后伤口感染风险因素:系统评价和荟萃分析。
Int Wound J. 2022 Nov;19(7):1748-1757. doi: 10.1111/iwj.13780. Epub 2022 Mar 1.
2
A Retrospective Chart Review of Skin Cancer Pattern and Clinical Outcomes Among Saudi Patients Visiting a Tertiary Care Hospital in Western Saudi Arabia From 1987-2016.1987年至2016年期间前往沙特阿拉伯西部一家三级护理医院就诊的沙特患者皮肤癌模式及临床结果的回顾性病历审查
Cureus. 2021 Dec 24;13(12):e20666. doi: 10.7759/cureus.20666. eCollection 2021 Dec.
3
Radiation therapy of cutaneous cancers.
皮肤癌的放射治疗。
Cancer Radiother. 2022 Feb-Apr;26(1-2):397-403. doi: 10.1016/j.canrad.2021.11.020. Epub 2021 Dec 23.
4
Lethal giant basal cell carcinoma.致命性巨大基底细胞癌。
Med Sci Law. 2022 Jan;62(1):70-73. doi: 10.1177/00258024211041792. Epub 2021 Sep 3.
5
[Place of radiotherapy in the treatment of cutaneous carcinomas].[放射治疗在皮肤癌治疗中的地位]
Cancer Radiother. 2021 Oct;25(6-7):593-597. doi: 10.1016/j.canrad.2021.07.006. Epub 2021 Aug 13.
6
Interventions for basal cell carcinoma of the skin.皮肤基底细胞癌的干预措施。
Cochrane Database Syst Rev. 2020 Nov 17;11(11):CD003412. doi: 10.1002/14651858.CD003412.pub3.
7
Super giant basal cell carcinoma in an autistic patient: A case report.一名自闭症患者的超大型基底细胞癌:病例报告
SAGE Open Med Case Rep. 2020 Jul 17;8:2050313X20939481. doi: 10.1177/2050313X20939481. eCollection 2020.
8
Different histopathologic profiles and outcomes between sun-exposed BCC and non-sun-exposed BCC.日光暴露部位基底细胞癌与非日光暴露部位基底细胞癌的不同组织病理学特征和结局。
Sci Rep. 2020 Apr 30;10(1):7387. doi: 10.1038/s41598-020-64391-9.
9
Versatility of the O-Z flap for back reconstruction after giant basal cell carcinoma resection: A case report and review of the literature.O-Z皮瓣在巨大基底细胞癌切除术后背部重建中的多功能性:一例报告及文献综述
Int J Surg Case Rep. 2019;63:23-26. doi: 10.1016/j.ijscr.2019.08.034. Epub 2019 Sep 11.
10
Giant basal cell carcinoma of the back: a case report and review of the literature.背部巨大基底细胞癌:一例报告并文献复习
Coll Antropol. 2009 Mar;33(1):315-8.