Liu Nana, Zheng Jun, Liu Tingting, Yan Hui, Ji Mengna, Liu Guang-Ning, Li Yunwu, Dou Jianmin, Yang Fei, Wang Suna
School of Chemistry and Chemical Engineering, University of Jinan, Jinan, Shandong 250022, P. R. China.
Shandong Provincial Key Laboratory of Chemical Energy Storage and Novel Cell Technology, School of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng 252059, P. R. China.
Inorg Chem. 2024 Oct 14;63(41):19117-19129. doi: 10.1021/acs.inorgchem.4c02497. Epub 2024 Oct 2.
Two Co(II) metal-organic frameworks (Co-MOFs), namely, [Co(DMTDC)(bimb)] () and {[Co(DPTDC)(bimb)(HO)]·2DMF} () (HDMTDC = 3,4-dimethylthieno[2,3-]thiophene-2,5-dicarboxylic acid, HDPTDC = 3,4-diphenylthieno[2,3-]thiophene-2,5-dicarboxylic acid, bimb = 1,4-bis((1-imidazol-1-yl)methyl)benzene), were obtained by the reaction of flexible N-containing ligand bimb and two structurally related thiophene-containing ligands HDMTDC and HDPTDC, respectively. These Co-MOFs displayed a 3D framework and porous structure, respectively. and the activated sample could act as green heterogeneous catalysts for the one-pot multicomponent Biginelli reaction, specifically the dehydration condensation process involving aldehydes, acetoacetates, and urea to yield dihydropyrimidin-2(1)-ones. The reaction has advantages such as solvent-free conditions, water as only byproduct, readily accessible starting materials, excellent functional group compatibility, and simple operation. Both catalysts exhibited a wide substrate scope and maintained significant catalytic activity over five cycles. The special catalytic performance may be ascribed to functional groups within the ligand.
通过柔性含氮配体1,4-双((1-咪唑-1-基)甲基)苯（bimb）分别与两种结构相关的含噻吩配体3,4-二甲基噻吩并[2,3-b]噻吩-2,5-二羧酸（HDMTDC）和3,4-二苯基噻吩并[2,3-b]噻吩-2,5-二羧酸（HDPTDC）反应，得到了两种钴（II）金属有机框架材料（Co-MOFs），即[Co(DMTDC)(bimb)]（ ）和{[Co(DPTDC)(bimb)(H₂O)]·2DMF}（ ）。这些Co-MOFs分别呈现出三维框架结构和多孔结构。活化后的样品 可作为绿色多相催化剂用于一锅多组分Biginelli反应，特别是涉及醛、乙酰乙酸酯和尿素脱水缩合生成二氢嘧啶-2(1H)-酮的过程。该反应具有无溶剂条件、仅以水作为副产物、起始原料易于获得、优异的官能团兼容性以及操作简单等优点。两种催化剂均具有广泛的底物范围，并且在五个循环中保持了显著的催化活性。这种特殊的催化性能可能归因于配体内的官能团。
