El-Mahrouk Mohamed, El-Shabrawi Azab, Langner Cord, Hau Hans Michael, Sucher Robert
Division of General, Visceral and Transplantation Surgery, Department of Surgery, Medical University of Graz, 8036 Graz, Austria.
Division of General, Visceral and Transplantation Surgery, Department of Surgery, Medical University of Graz, 8036 Graz, Austria.
Int J Surg Case Rep. 2024 Nov;124:110364. doi: 10.1016/j.ijscr.2024.110364. Epub 2024 Sep 30.
Papillary adenomas are very rare benign tumors of the gastrointestinal tract. If manageable, purely endoscopic resection is favored. As an alternative, surgical resection via ampullectomy or pancreaticoduodenectomy can be performed. Often, the depth of infiltration cannot be assessed with sufficient precision, leading to pancreaticoduodenectomy for safety reasons.
We present the case of a 77-year-old patient in whom a transduodenal papillary resection of a large papillary adenoma was performed, after two unsuccessful endoscopic attempts. Intraoperatively, a 3 cm large papillary adenoma was identified in the duodenum. The infiltration depth into the Vater's papilla was evaluated through intraoperative cholangioscopy. Due to the shallow depth of invasion, we strived for a papillary resection under endoscopic guidance, allowing complete tumor removal. The postoperative course was uneventful, and the patient was discharged on postoperative day 14.
The decision between ampullectomy and pancreaticoduodenectomy is an intraoperative challenge. Intraoperative cholangioscopy demonstrated its potential to aid this decision-making process in this case. Larger-scale studies are needed to establish its clinical value.
Intraoperative cholangiography can help surgeons assess the depth of infiltration of large papillary adenomas, leading to more precise surgical decisions about the necessary extent of resection.
乳头状腺瘤是非常罕见的胃肠道良性肿瘤。如果可以处理,首选单纯内镜下切除。作为替代方案,可通过壶腹切除术或胰十二指肠切除术进行手术切除。通常,浸润深度无法得到足够精确的评估,出于安全考虑往往需行胰十二指肠切除术。
我们报告一例77岁患者,在内镜检查两次尝试失败后,对其十二指肠大乳头状腺瘤进行了经十二指肠乳头状切除术。术中,在十二指肠发现一个3厘米大的乳头状腺瘤。通过术中胆管镜评估其向 Vater 乳头的浸润深度。由于浸润深度较浅,我们争取在内镜引导下进行乳头状切除,实现肿瘤完整切除。术后过程顺利,患者于术后第14天出院。
壶腹切除术和胰十二指肠切除术之间的抉择是术中面临的一项挑战。术中胆管镜显示其在本病例中有助于这一决策过程。需要开展更大规模的研究来确定其临床价值。
术中胆管造影可帮助外科医生评估大乳头状腺瘤的浸润深度,从而就必要的切除范围做出更精确的手术决策。