Seki Yoshinobu
Department of Hematology, Niigata University Medical and Dental Hospital.
Rinsho Ketsueki. 2024;65(9):1094-1100. doi: 10.11406/rinketsu.65.1094.
Disseminated intravascular coagulation (DIC) is defined as systemic intravascular coagulation activity that has been acquired in the presence of various underlying diseases and is outside local or compensatory control, and is a fatal condition. Although the pathogenesis, diagnosis, and treatment of DIC are well known in Japan, each clinician has a different understanding of DIC, which makes it difficult to standardize diagnosis and treatment. Even at the international level, perception of DIC varies widely. This makes it difficult for residents and novice clinicians to standardize routine care for DIC. To meet the demands of the times, my colleagues and I are currently working on a globally unprecedented project to develop guidelines for the treatment of DIC for each underlying disease (tentative title). This article will also review the status of past guidelines from inside and outside Japan.
弥散性血管内凝血(DIC)被定义为在各种基础疾病存在的情况下所发生的全身性血管内凝血活性,且不受局部或代偿性控制,是一种致命性病症。尽管在日本,DIC的发病机制、诊断和治疗已广为人知,但每位临床医生对DIC的理解各不相同,这使得诊断和治疗难以标准化。即使在国际层面,对DIC的认知也存在很大差异。这使得住院医师和新手临床医生难以对DIC的常规护理进行标准化。为了满足时代需求,我和我的同事目前正在开展一个全球前所未有的项目,即针对每种基础疾病制定DIC治疗指南(暂定标题)。本文还将回顾日本国内外过去指南的情况。