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新型人免疫球蛋白SM - 4300对手术患者严重感染的治疗作用

[Therapeutic effect of a new human immunoglobulin SM-4300 on the severe infections in surgical patients].

作者信息

Nakayama I, Kawaguchi H, Yamaji E, Akieda Y, Itokawa K

出版信息

Jpn J Antibiot. 1985 Sep;38(9):2617-21.

PMID:3935829
Abstract

A newly developed human immunoglobulin preparation for intravenous use, SM-4300, had been studied in the field of surgery. SM-4300 was administered to 2 patients with severe infection in the combined use with antibiotics. SM-4300 was considered to be a safe and effectively useful drug. One case with suspicious of septicaemia was excellent response to SM-4300, at a dosage of 2.5 g/day x 3, and another case with postoperative diffuse peritonitis was not effective at a dosage of 5.0 g/day x 1. No objective and subjective side effect and abnormal laboratory finding was observed in 2 cases.

摘要

一种新研发的静脉用人免疫球蛋白制剂SM - 4300已在外科领域进行了研究。将SM - 4300与抗生素联合用于2例严重感染患者。SM - 4300被认为是一种安全且有效的药物。1例疑似败血症患者以2.5克/天×3的剂量使用SM - 4300后反应良好,而另1例术后弥漫性腹膜炎患者以5.0克/天×1的剂量使用则无效。2例患者均未观察到客观和主观的副作用以及实验室检查异常结果。

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