Ayabe H, Shimizu T, Mori M, Ishii T, Shimoyama T, Miura T, Tomita M, Nakao S, Taniguchi H, Noguchi K
Jpn J Antibiot. 1985 Sep;38(9):2665-72.
SM-4300, a newly developed human immunoglobulin preparation, has been studied for the safety and effectiveness/efficacy in the 16 patients with severe bacterial and/or fungal infections which are resistant to antibiotic therapy. Clinical effect of 16 cases were excellent 1 case, good 4, fair 4, poor 4 and unknown 3. The efficacy rate was 38.5% and the efficacy rate including fair was 69.2%. No remarkable adverse reaction due to administration of SM-4300 were observed.
SM - 4300是一种新研发的人免疫球蛋白制剂,已针对16例对抗生素治疗耐药的严重细菌和/或真菌感染患者进行了安全性和有效性研究。16例患者的临床疗效为:优1例,良4例,中4例,差4例,不明3例。有效率为38.5%,包括中在内的有效率为69.2%。未观察到因使用SM - 4300而出现的明显不良反应。