[Synergism of the anti-anginal action of beta-blockers and calcium antagonists in patients with ischemic heart disease].

A variety of anti-anginal drugs and their combinations were selected in a group of patients with stable angina of effort, with the effects assessed by bicycle ergometry. Effective doses of propranolol, corinfar, finoptin provided for at least 3 minutes' increment in the duration of the effort. Combinations of these drugs in doses reduced by half produced a more pronounced increment in the duration of the effort, an observation suggestive of synergistic anti-anginal effects of calcium antagonists and beta-blockers.