Karaki Victoria Al, Saab Aed
Department of Emergency Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Int J Emerg Med. 2024 Oct 2;17(1):132. doi: 10.1186/s12245-024-00724-z.
Penetrating aortic ulcers (PAU) are life-threatening conditions which derive from severely advanced atherosclerotic lesions of the aorta. The clinical course is unpredictable; thus clinical vigilance should be maintained. It is very challenging to separate PAU from co-existing AAS as predisposing factors and findings overlap.
Case of 58-year-old gentleman, who presented for atypical chest pain in the setting of respiratory tract infection. Computed Tomographic angiography (CTA) of the chest showed a large PAU and intramural hematoma which rapidly progressed into an acute aortic dissection in the emergency department. Close follow up with cardiac point of care ultrasound one hour later detected an intimal flap which was not initially present on CTA. Patient underwent surgical aortic graft replacement and had an uneventful in-hospital stay.
This case underlines the importance of broadening differential diagnoses in atypical presentations in patients with risk factors. Prompt intervention and careful management are imperative to optimize patient outcomes and prevent complications of aortic lesions. Cardiac point of care ultrasound can help in detecting progression of dynamic atherosclerotic diseases such as acute aortic syndrome.
穿透性主动脉溃疡(PAU)是源于严重进展性主动脉粥样硬化病变的危及生命的疾病。其临床病程不可预测,因此应保持临床警惕。由于易感因素和检查结果重叠,将PAU与并存的急性主动脉综合征(AAS)区分开来极具挑战性。
一名58岁男性患者,因呼吸道感染出现非典型胸痛前来就诊。胸部计算机断层血管造影(CTA)显示一个大的PAU和壁内血肿,在急诊科迅速发展为急性主动脉夹层。一小时后通过心脏床旁超声密切随访发现了一个最初在CTA上未出现的内膜瓣。患者接受了主动脉移植手术,住院期间病情平稳。
该病例强调了在有危险因素的患者非典型表现中扩大鉴别诊断的重要性。及时干预和谨慎管理对于优化患者预后及预防主动脉病变并发症至关重要。心脏床旁超声有助于检测急性主动脉综合征等动态动脉粥样硬化疾病的进展。