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终板不同损伤形态对椎间盘退变的影响:回顾性队列研究。

Effect of Different Injury Morphology of the Endplate on Intervertebral Disc Degeneration: Retrospective Cohort Study.

机构信息

Department of Traumatic Orthopedics, Suizhou Hospital, Hubei University of Medicine, Suizhou, Hubei, China.

Wuhan University of Science and Technology, Wuhan, Hubei, China.

出版信息

Orthop Surg. 2024 Dec;16(12):2995-3005. doi: 10.1111/os.14238. Epub 2024 Oct 2.

Abstract

OBJECTIVES

To describe a simplified classification scheme for endplate injury morphology based on 3D CT and to examine possible associations between endplate injury morphology and vertebral space and other variables such as type of fracture and disc degeneration in a group of patients with thoracolumbar fractures.

METHODS

This study was a retrospective cohort study. We collected patients with thoracolumbar fractures admitted from January 2015 to August 2020 and divided them into three groups based on the morphology of endplate injury (45 cases of mild endplate injury, 54 cases of moderate endplate injury, and 42 cases of severe endplate injury, SEI). Data of vertebral body and intervertebral space height and angle, the Pfirrmann grade, endplate healing morphology were collected during preoperative, postoperative, and long-term follow-up of patients in each group. One-way analysis of variance (ANOVA), chi-squared test, and repeated measurement ANOVA were used to compare and analyze the influence of endplate injury morphology on patient prognosis.

RESULTS

Most moderate injuries to the endplate (fissure-type injury) and severe injuries (irregular depression-type injury, Schmorl's node-type injury) resulted in significant disc degeneration in the long-term transition. This study also showed significant differences in the height of the anterior margin of the injured spine and the intervertebral space height index during this process.

CONCLUSIONS

The current study suggests that although the region of injury in endplate fissure-type injury is small preoperatively, it may be a major factor in leading to severe disc degeneration, loss of intervertebral height, and Cobb angle in the long term. The results of our study therefore may allow surgeons to predict the prognosis of patients with thoracolumbar fractures and guide their treatment.

摘要

目的

基于 3D CT 描述一种简单的终板损伤形态分类方案,并研究胸腰椎骨折患者中终板损伤形态与椎间隙和其他变量(如骨折类型和椎间盘退变)之间的可能关联。

方法

本研究为回顾性队列研究。我们收集了 2015 年 1 月至 2020 年 8 月收治的胸腰椎骨折患者,并根据终板损伤形态将其分为三组(轻度终板损伤 45 例,中度终板损伤 54 例,重度终板损伤 42 例,SEI)。在每组患者术前、术后和长期随访期间收集椎体和椎间隙高度和角度、Pfirrmann 分级、终板愈合形态等数据。采用单因素方差分析(ANOVA)、卡方检验和重复测量 ANOVA 对终板损伤形态对患者预后的影响进行比较和分析。

结果

大多数中度终板损伤(裂隙型损伤)和重度损伤(不规则凹陷型损伤、Schmorl 结节型损伤)在长期转变过程中导致明显的椎间盘退变。本研究还表明,在这个过程中,受伤脊柱前缘高度和椎间隙高度指数有显著差异。

结论

目前的研究表明,尽管术前终板裂隙型损伤的损伤区域较小,但可能是导致严重椎间盘退变、椎间隙高度丧失和 Cobb 角的主要因素。因此,我们的研究结果可能使外科医生能够预测胸腰椎骨折患者的预后,并指导治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba61/11608786/63c9f7f6abea/OS-16-2995-g006.jpg

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