Bode Felix J, Zadon Nina A, Asperger Hannah, Beckonert Niklas M, Ebrahimi Taraneh, Nitsch Louisa, Nordsiek Julia, Meissner Julius N, Shirvani Omid, Stösser Sebastian, Thielscher Christian, Dorn Franziska, Lehnen Nils C, Petzold Gabor C, Weller Johannes M
Department of Vascular Neurology, Center of Neurology, University Hospital Bonn, Bonn, Germany.
Department of Neuroradiology, University Hospital Bonn, Bonn, Germany.
Eur Stroke J. 2024 Oct 3:23969873241282875. doi: 10.1177/23969873241282875.
Endovascular thrombectomy (EVT) combined with intravenous thrombolysis is the current standard treatment for acute large-vessel occlusion stroke. Beyond clear clinical benefits in the acute and post-acute phases, comprehensive evaluations of long-term outcomes, including home and workforce reintegration, remain limited. This study aimed to assess home and workforce reintegration 1 year post-EVT in a cohort of acute stroke patients and explore their association with health-related quality of life (HRQoL).
We conducted a prospective observational study of 404 patients undergoing EVT at a tertiary university medical center between October 2019 and December 2021. Patients' functional outcomes were evaluated using the modified Rankin Scale (mRS), and HRQoL was assessed via the European Quality of Life Five Dimension Scale (EQ-5D). Data on occupational and living status were collected through standardized telephone interviews at 3- and 12-months post-treatment.
Of 357 patients with 12-month follow-up data, 33.6% had a favorable outcome (mRS 0-2). Among stroke survivors, the rate of home reintegration without nursing care was 42.1%, and workforce reintegration among previously employed patients was 43.3% at 12 months. Both outcomes were significantly associated with improved HRQoL. Lower neurological deficits and younger age were predictive of successful home and workforce reintegration.
One year post-EVT, approximately 40%-50% of acute stroke patients successfully reintegrate into home and work settings. These findings underscore the need for ongoing support tailored to improving long-term reintegration and quality of life for stroke survivors.
The data supporting the findings of the study are available from the corresponding author upon reasonable request and in accordance to European data privacy obligations.
血管内血栓切除术（EVT）联合静脉溶栓是目前急性大血管闭塞性卒中的标准治疗方法。除了在急性期和亚急性期有明确的临床益处外，对包括家庭和重返工作岗位在内的长期结局的综合评估仍然有限。本研究旨在评估一组急性卒中患者在接受EVT治疗1年后的家庭和重返工作岗位情况，并探讨它们与健康相关生活质量（HRQoL）的关联。
我们对2019年10月至2021年12月期间在一所三级大学医学中心接受EVT治疗的404例患者进行了一项前瞻性观察研究。使用改良Rankin量表（mRS）评估患者的功能结局，并通过欧洲生活质量五维度量表（EQ-5D）评估HRQoL。通过标准化电话访谈在治疗后3个月和12个月收集职业和生活状况数据。
在357例有12个月随访数据的患者中，33.6%有良好结局（mRS 0-2）。在卒中幸存者中，12个月时无需护理即可重返家庭的比例为42.1%，之前就业的患者重返工作岗位的比例为43.3%。这两种结局均与HRQoL改善显著相关。较低的神经功能缺损和较年轻的年龄是成功重返家庭和工作岗位的预测因素。
EVT治疗1年后，约40%-50%的急性卒中患者成功重返家庭和工作岗位。这些发现强调了需要持续提供针对性支持，以改善卒中幸存者的长期重返社会情况和生活质量。
支持本研究结果的数据可根据合理要求并按照欧洲数据隐私义务从相应作者处获取。
