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尽量减少不必要的脑钠肽血液检测:对全科医疗中弹出式表单实施情况的评估。

Minimizing unnecessary proBNP blood tests: an evaluation of a pop-up form implementation in general practice.

作者信息

Esmaeilzadeh Morvarid Sophia, Engell Anna Elise, Jørgensen Henrik Løvendahl, Lind Bent Struer

机构信息

Department of Clinical Biochemistry, Copenhagen University Hospital, Hvidovre, Denmark.

Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.

出版信息

Scand J Prim Health Care. 2025 Mar;43(1):148-154. doi: 10.1080/02813432.2024.2410984. Epub 2024 Oct 3.

DOI:10.1080/02813432.2024.2410984
PMID:39359235
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11834815/
Abstract

OBJECTIVE

To evaluate the impact of a compulsory pop-up form on the ordering pattern of proBNP blood tests by general practitioners in the Capital Region of Denmark.

DESIGN

A follow-up study comparing the average number of proBNP tests ordered before and after the implementation of an intervention.

SETTING AND SUBJECTS

From 2016 to 2021, the average number of proBNP tests increased by over 300%. In March 2022, a compulsory pop-up form was introduced in the electronic request system (WebReq), requiring general practitioners to select one of three indications for ordering proBNP, as recommended by the Danish Society of Cardiology. The study included 528 general practitioners in the Capital Region of Denmark, with data available from January 2020 to 2023, encompassing 83,576 proBNP results from 56,645 patients.

MAIN OUTCOME MEASURE

The average number of proBNP tests ordered per month and the median level of proBNP before and after the intervention.

RESULTS

Following the intervention, the average number of proBNP tests per month decreased by 60% over a 22-month follow-up period. The highest reduction was seen among general practitioners who previously ordered the most tests (≥3 per 1000 biochemical tests). In this group, the median proBNP level increased from 12.1 pmol/L before the intervention to 13.5 pmol/L after the intervention ( < 0.0001).

CONCLUSIONS

This study demonstrates a significant decrease in the number of proBNP requests from general practitioners in the Capital Region of Denmark after the introduction of a pop-up form in the requisition system containing the current guidelines.

摘要

目的

评估强制弹出式表单对丹麦首都地区全科医生检测血浆脑钠肽(proBNP)血液检测订单模式的影响。

设计

一项随访研究,比较干预实施前后proBNP检测的平均数量。

设置与研究对象

2016年至2021年,proBNP检测的平均数量增加了300%以上。2022年3月,电子请求系统(WebReq)中引入了强制弹出式表单,要求全科医生按照丹麦心脏病学会的建议,从三种检测proBNP的指征中选择一种。该研究纳入了丹麦首都地区的528名全科医生,数据来自2020年1月至2023年,涵盖了56645名患者的83576份proBNP检测结果。

主要观察指标

干预前后每月订购的proBNP检测平均数量以及proBNP的中位数水平。

结果

干预后,在22个月的随访期内,每月proBNP检测的平均数量下降了60%。在之前检测次数最多(每1000次生化检测中≥3次)的全科医生中,下降幅度最大。在这一组中,proBNP的中位数水平从干预前的12.1 pmol/L升至干预后的13.5 pmol/L(<0.0001)。

结论

本研究表明,在申请系统中引入包含现行指南的弹出式表单后,丹麦首都地区全科医生申请proBNP检测的数量显著减少。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63b6/11834815/25896ca40036/IPRI_A_2410984_F0002_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63b6/11834815/2ddb1fbfeb02/IPRI_A_2410984_F0001_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63b6/11834815/25896ca40036/IPRI_A_2410984_F0002_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63b6/11834815/2ddb1fbfeb02/IPRI_A_2410984_F0001_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63b6/11834815/25896ca40036/IPRI_A_2410984_F0002_C.jpg

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本文引用的文献

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Crit Care Med. 2023 Jun 1;51(6):717-730. doi: 10.1097/CCM.0000000000005852. Epub 2023 Mar 23.
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2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: Developed by the Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC). With the special contribution of the Heart Failure Association (HFA) of the ESC.2021 ESC 急性和慢性心力衰竭诊断和治疗指南:由欧洲心脏病学会(ESC)急性和慢性心力衰竭诊断和治疗工作组制定。特别感谢欧洲心脏病学会心力衰竭协会(HFA)的贡献。
Eur J Heart Fail. 2022 Jan;24(1):4-131. doi: 10.1002/ejhf.2333.
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N-terminal pro-B-type natriuretic peptide testing patterns in patients with heart failure with reduced ejection fraction.心力衰竭伴射血分数降低患者的 N 末端 pro-B 型利钠肽检测模式。
ESC Heart Fail. 2022 Feb;9(1):87-99. doi: 10.1002/ehf2.13749. Epub 2021 Dec 16.
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The 10 most frequently requested blood tests in the Capital Region of Denmark, 2010-2019 and simulated effect of minimal retesting intervals.丹麦首都地区2010 - 2019年最常要求进行的10项血液检测以及最小复检间隔的模拟效果。
Clin Biochem. 2022 Feb;100:55-59. doi: 10.1016/j.clinbiochem.2021.11.002. Epub 2021 Nov 11.
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Potential pitfalls when interpreting plasma BNP levels in heart failure practice.在心力衰竭诊疗中解读血浆脑钠肽水平时的潜在陷阱。
J Cardiol. 2021 Oct;78(4):269-274. doi: 10.1016/j.jjcc.2021.05.003. Epub 2021 Jun 2.
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