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大数据在老年肿瘤学研究中的应用

Big Data for Geriatric Oncology Research.

机构信息

Department of Epidemiology and Prevention, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina.

Section on Hematology and Oncology, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina.

出版信息

N C Med J. 2024;85(1):20-24. doi: 10.18043/001c.91420. Epub 2024 Jan 9.

DOI:10.18043/001c.91420
PMID:39359617
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11444596/
Abstract

Cancer is the second leading cause of death in North Carolina and approximately half of cancers are diagnosed in older adults (≥65 years). Cancer clinical trials in older adults are limited and there is a lack of evidence on optimal care strategies in this population. We highlight how big data can fill in gaps in geriatric oncology research.

摘要

癌症是北卡罗来纳州的第二大死因，大约一半的癌症发生在老年人（≥65 岁）中。老年人的癌症临床试验有限，并且在该人群中缺乏最佳护理策略的证据。我们强调了大数据如何填补老年肿瘤学研究中的空白。

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本文引用的文献

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Prognosis of older adults with chronic lymphocytic leukemia: A Surveillance, Epidemiology, and End Results-Medicare cohort study.老年慢性淋巴细胞白血病患者的预后：监测、流行病学和最终结果-医疗保险队列研究。
J Geriatr Oncol. 2023 Nov;14(8):101602. doi: 10.1016/j.jgo.2023.101602. Epub 2023 Sep 9.
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Practical Assessment and Management of Vulnerabilities in Older Patients Receiving Systemic Cancer Therapy: ASCO Guideline Update.老年癌症系统治疗患者脆弱性的实用评估与管理：ASCO 指南更新。
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Assessment of an embedded primary care-derived electronic health record (EHR) frailty index (eFI) in older adults with acute myeloid leukemia.评估老年急性髓系白血病患者中源自嵌入式初级保健的电子健康记录（EHR）衰弱指数（eFI）。
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Associations of interleukin-6 with functional trajectories in older adults with cancer: Findings from the Health, Aging, and Body Composition Study.白细胞介素-6 与老年癌症患者功能轨迹的相关性：来自健康、衰老和身体成分研究的结果。
Exp Gerontol. 2023 Jun 15;177:112185. doi: 10.1016/j.exger.2023.112185. Epub 2023 Apr 29.
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Update on Enrollment of Older Adults Onto National Cancer Institute National Clinical Trials Network Trials.老年患者参与美国国立癌症研究所国家临床试验网络试验的最新进展。
J Natl Cancer Inst Monogr. 2022 Dec 15;2022(60):111-116. doi: 10.1093/jncimonographs/lgac017.
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An Overview of Cancer in the First 315,000 All of Us Participants.《在所有 31.5 万名“我们所有人”参与者中癌症概述》。
PLoS One. 2022 Sep 1;17(9):e0272522. doi: 10.1371/journal.pone.0272522. eCollection 2022.
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