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滑膜肉瘤的罕见表现:一例β-HCG水平升高的罕见病例报告

Unusual manifestation of synovial sarcoma: A rare case report with elevated beta HCG level.

作者信息

Khosh Elnaz, Kazemi Arya, Abbaspour Elahe, Vahdati Sanaz, Mirenayat Maryam Sadat, Ghaderi-Sohi Siavash, Haseli Sara, Askari Elham

机构信息

Department of Radiology, Zanjan University of Medical Sciences, Zanjan, Iran.

Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Radiol Case Rep. 2024 Aug 26;19(11):5262-5267. doi: 10.1016/j.radcr.2024.07.178. eCollection 2024 Nov.

Abstract

Synovial sarcoma is a rare type of soft tissue sarcoma that typically arises in the lower extremities and rarely in the upper extremities. Here, we present an unusual case of a middle-aged man who complained of dyspnea, dry cough, and chest pain and was found to have a mass-like lesion on the ulnar side of his left wrist during physical examination. The patient also exhibited gynecomastia and had elevated β-human chorionic gonadotropin (βHCG) levels. Subsequent imaging and histopathological analysis of the wrist mass confirmed the diagnosis of synovial sarcoma with disseminated lung metastasis. This article aims to provide a comprehensive overview of the clinical and pathological characteristics of synovial sarcoma, highlight the importance of considering synovial sarcoma as a differential diagnosis in patients with abnormal hormonal assays, and emphasize the need for clinicians to be vigilant about any pathologic lesions existing on the upper extremity to avoid late diagnosis and the development of advanced cancerous diseases.

摘要

滑膜肉瘤是一种罕见的软组织肉瘤,通常发生在下肢,很少发生在上肢。在此,我们报告一例不寻常的病例,一名中年男性主诉呼吸困难、干咳和胸痛,体格检查发现其左手腕尺侧有一个肿块样病变。该患者还出现了男性乳房发育,且β-人绒毛膜促性腺激素(βHCG)水平升高。随后对腕部肿块进行的影像学和组织病理学分析证实为滑膜肉瘤伴肺转移。本文旨在全面概述滑膜肉瘤的临床和病理特征,强调在激素检测异常的患者中考虑滑膜肉瘤作为鉴别诊断的重要性,并强调临床医生需要对上肢存在的任何病理性病变保持警惕,以避免晚期诊断和晚期癌症疾病的发生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/85c8/11445589/7a31c4726258/gr1.jpg

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