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揭示罕见病例:一例酷似舌下囊肿的低分化滑膜肉瘤病例报告

Unveiling Rarity: A Case Report of a Poorly Differentiated Synovial Sarcoma Mimicking a Plunging Ranula.

作者信息

Sanchez Jorge, Guevara Nehemias, Chapiolkina Volha, Perez Rosario Esmirna M, Tole Maria C, Mekonen Yemesrach, Fulger Ilmana

机构信息

Internal Medicine, St. Barnabas Hospital Health System, New York, USA.

Hematology-Oncology, St. Barnabas Hospital Health System, New York, USA.

出版信息

Cureus. 2024 Jul 10;16(7):e64290. doi: 10.7759/cureus.64290. eCollection 2024 Jul.

Abstract

Synovial sarcomas are uncommon and highly aggressive sarcomas. Typically, they start in the soft tissues of the extremities, although they may develop in the head and neck region in rare cases. When they do, they usually present with localized symptoms in the affected area. Our patient is a 20-year-old man without a medical history who complained of a three-month history of submental swelling of the left side with a non-tender, palpable 5 cm mass. Initially believed to be a plunging ranula, the patient underwent transoral excision of the left submandibular soft tissue mass in the neck by the ear, nose, and throat (ENT) specialist. The pathological analysis of the mass confirmed the presence of a poorly differentiated synovial sarcoma. A postoperative neck imaging was performed, which showed a significant decrease in mass size compared to the previous imaging; however, the mass was still present. This is one of the few described cases of a poorly differentiated synovial sarcoma located on the floor of the mouth. Therefore, it highlights the importance of considering it as a possible differential diagnosis of head and neck pathologies.

摘要

滑膜肉瘤是一种罕见且侵袭性很强的肉瘤。通常,它们起始于四肢的软组织,不过在极少数情况下也可能发生于头颈部区域。一旦发生在头颈部,通常会在受累部位出现局部症状。我们的患者是一名20岁男性,无病史,主诉左侧颏下肿胀3个月,可触及一个5厘米大小的无痛性肿块。最初被认为是舌下囊肿,患者由耳鼻喉科(ENT)专家经口切除了颈部左侧下颌下软组织肿块。肿块的病理分析证实为低分化滑膜肉瘤。术后进行了颈部影像学检查,结果显示与之前的影像相比,肿块大小显著减小;然而,肿块仍然存在。这是少数几例位于口底的低分化滑膜肉瘤病例之一。因此,它凸显了将其作为头颈部病变可能的鉴别诊断加以考虑的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb5b/11241640/c52d5db120cf/cureus-0016-00000064290-i01.jpg

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