Reddy Sunya, Molleti Madhuri, Li Li
Department of Psychiatry and Behavioral Neurobiology, Li Laboratory, University of Alabama at Birmingham, Birmingham, AL, USA.
Alpha Psychiatry. 2024 Aug 1;25(4):513-518. doi: 10.5152/alphapsychiatry.2024.231435. eCollection 2024 Aug.
The study aimed to evaluate negative and positive emotional responses to acute psychological stress in individuals with early life stress (ELS).
One hundred sixty-one participants from the Birmingham community in Alabama completed the study and were stratified into 2 groups based on measurements of ELS using the Childhood Trauma Questionnaire and a confirmatory clinical interview. Acute psychological stress, that is, the Trier Social Stress Test (TSST), was administered, and emotional responses were measured using the Visual Analogue Scale. Comparisons utilized chi-square for categorical variables and -test for continuous variables. Analysis of covariance (ANCOVA) was applied to compare the 2 groups after controlling for confounding variables. Stepwise multiple linear regression analysis was used to investigate predictive power of variables for emotional responses to the TSST.
Participants with ELS experienced less pleasantness at the baseline ( = .02), and 1 minute ( = .04), but not 90 minutes time points compared to the non-ELS group. Participants in the ELS group also reported higher anxiety at baseline ( = .003), and 90 minutes ( = .04) post-TSST. Data analysis showed the effect of time on emotional responses during the TSST. Different emotional responses, including pleasantness, anxiety, fatigue, and vigor, were able to be predicted by ELS severity.
Our data demonstrates that individuals with ELS presented different positive and negative emotional responses when exposed to acute psychological stress. Our findings may be useful for clinicians who work with individuals with ELS. Our findings also highlight the importance of recognizing emotional responses and of building up resilience in response to acute stress.
本研究旨在评估早年生活应激(ELS)个体对急性心理应激的消极和积极情绪反应。
来自阿拉巴马州伯明翰社区的161名参与者完成了该研究,并根据使用儿童创伤问卷和确认性临床访谈对ELS的测量结果分为两组。实施急性心理应激,即特里尔社会应激测试(TSST),并使用视觉模拟量表测量情绪反应。分类变量比较采用卡方检验,连续变量比较采用t检验。协方差分析(ANCOVA)用于在控制混杂变量后比较两组。逐步多元线性回归分析用于研究变量对TSST情绪反应的预测能力。
与非ELS组相比,ELS参与者在基线时(p = 0.02)和1分钟时(p = 0.04)体验到的愉悦感较低,但在90分钟时间点时没有差异。ELS组的参与者在基线时(p = 0.003)和TSST后90分钟(p = 0.04)也报告了更高的焦虑水平。数据分析显示了TSST期间时间对情绪反应的影响。ELS严重程度能够预测不同的情绪反应,包括愉悦感、焦虑、疲劳和活力。
我们的数据表明,ELS个体在暴露于急性心理应激时表现出不同的积极和消极情绪反应。我们的发现可能对与ELS个体合作的临床医生有用。我们的发现还强调了识别情绪反应以及建立应对急性应激的恢复力的重要性。