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治疗脂溢性皮炎的皮肤科治疗方法。

Dermatologic Procedures for the Treatment of Seborrheic Dermatitis.

出版信息

J Drugs Dermatol. 2024 Oct 1;23(10):819-824. doi: 10.36849/JDD.2024.8116.

Abstract

BACKGROUND

This paper examines alternative procedural interventions for Seborrheic Dermatitis (SD), aiming to offer clinicians more treatment options and encourage further research.

METHOD

A search was conducted on PubMed using specific search terms related to SD and various dermatological procedures. Studies in English, focusing on SD in human patients, and in-office treatments were included. Data were analyzed for procedure type, effectiveness, and side effects.

RESULTS

Nine studies were reviewed, covering phototherapy, indole-3-acetic acid photodynamic therapy (IAA-PDT), Picosecond Nd:YAG laser, botulinum toxin (BoNT) injections, triamcinolone injections, hair growth factor therapy, and precision cryotherapy. Most showed significant efficacy in small cohorts with high patient satisfaction. Hair growth factor therapy had long-term benefits, while narrow-band ultraviolet B phototherapy showed relapse within one month. Intense pulsed light with supramolecular salicylic acid, IAA-PDT, and laser therapy reduced sebum output and Malassezia furfur. Triamcinolone injections were effective against SD's immunological aspects. Hair growth factor therapy and precision cryotherapy have been successfully used to treat scalp SD. The role of BoNT in SD is still being explored; however, current evidence does not support its use.

CONCLUSION

Limited data reveal the need for further research on dermatological procedures for SD. These methods show promise for better patient compliance but face challenges such as cost, variable effectiveness, and unknown long-term safety. Future research should focus on protocol standardization and comprehensive evaluation of long-term outcomes. J Drugs Dermatol. 2024;23(10):819-824. doi:10.36849/JDD.8116.

摘要

背景

本文探讨了治疗脂溢性皮炎(SD)的替代方法,旨在为临床医生提供更多的治疗选择,并鼓励进一步的研究。

方法

使用与 SD 和各种皮肤科程序相关的特定搜索词在 PubMed 上进行了搜索。纳入了研究对象为人类患者且为门诊治疗的英语研究。对程序类型、疗效和副作用进行数据分析。

结果

共综述了 9 项研究,涵盖了光疗、吲哚-3-乙酸光动力疗法(IAA-PDT)、皮秒 Nd:YAG 激光、肉毒毒素(BoNT)注射、曲安奈德注射、毛发生长因子治疗和精准冷冻疗法。大多数研究在小队列中显示出显著疗效,患者满意度高。毛发生长因子治疗具有长期获益,而窄带紫外线 B 光疗在一个月内复发。强脉冲光联合超分子水杨酸、IAA-PDT 和激光疗法可减少皮脂分泌和糠秕马拉色菌。曲安奈德注射对 SD 的免疫方面有效。毛发生长因子治疗和精准冷冻疗法已成功用于治疗头皮 SD。BoNT 在 SD 中的作用仍在探索中;然而,目前的证据并不支持其使用。

结论

有限的数据表明需要进一步研究治疗 SD 的皮肤科程序。这些方法显示出提高患者依从性的潜力,但面临成本、疗效变化和未知长期安全性等挑战。未来的研究应侧重于方案标准化和对长期结果的综合评估。J 皮肤病药物杂志。2024;23(10):819-824. doi:10.36849/JDD.8116.

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